dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0006774 |
| Uniprot Accession | P20815; CP3A5_HUMAN; A4D289; B7Z5I7; Q53WY8; Q75MV0; Q9HB56; |
| Genbank Protein ID | NP_000768.1; NP_001177413.1; |
| Genbank Nucleotide ID | NM_000777.4; NM_001190484.2; |
| Protein Name | Cytochrome P450 3A5 |
| Protein Synonyms/Alias | CYPIIIA5;Cytochrome P450 HLp2;Cytochrome P450-PCN3; |
| Gene Name | CYP3A5 |
| Gene Synonyms/Alias | |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MDLIPNLAVE TWLLLAVSLV LLYLYGTRTH GLFKRLGIPG PTPLPLLGNV LSYRQGLWKF 60 DTECYKKYGK MWGTYEGQLP VLAITDPDVI RTVLVKECYS VFTNRRSLGP VGFMKSAISL 120 AEDEEWKRIR SLLSPTFTSG KLKEMFPIIA QYGDVLVRNL RREAEKGKPV TLKDIFGAYS 180 MDVITGTSFG VNIDSLNNPQ DPFVESTKKF LKFGFLDPLF LSIILFPFLT PVFEALNVSL 240 FPKDTINFLS KSVNRMKKSR LNDKQKHRLD FLQLMIDSQN SKETESHKAL SDLELAAQSI 300 IFIFAGYETT SSVLSFTLYE LATHPDVQQK LQKEIDAVLP NKAPPTYDAV VQMEYLDMVV 360 NETLRLFPVA IRLERTCKKD VEINGVFIPK GSMVVIPTYA LHHDPKYWTE PEEFRPERFS 420 KKKDSIDPYI YTPFGTGPRN CIGMRFALMN MKLALIRVLQ NFSFKPCKET QIPLKLDTQG 480 LLQPEKPIVL KVDSRDGTLS GE 503 |
| Keyword | KW-0025--Alternative splicing |
| Interpro | IPR001128--Cyt_P450 |
| PROSITE | PS00086--CYTOCHROME_P450 |
| Pfam | PF00067--p450 |
| Gene Ontology | GO:0005789--C:endoplasmic reticulum membrane |