dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006665
Uniprot Accession P20081; FKBP_YEAST; D6W147;
Genbank Protein ID NP_014264.1;
Genbank Nucleotide ID NM_001182973.1;
Protein Name FK506-binding protein 1
Protein Synonyms/Alias
Gene Name FPR1
Gene Synonyms/Alias FKB1;RBP1;YNL135C;N1213;N1845;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
15NVKIDRISPGDGATFcurated24961812
34DLVTIHYTGTLENGQcurated22817900; 24961812
36VTIHYTGTLENGQKFcurated22817900
45ENGQKFDSSVDRGSPcurated19823750; 25315811
46NGQKFDSSVDRGSPFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 20377248
51DSSVDRGSPFQCNIGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 19779198;
Sequence
(Fasta)		MSEVIEGNVK IDRISPGDGA TFPKTGDLVT IHYTGTLENG QKFDSSVDRG SPFQCNIGVG 60
QVIKGWDVGI PKLSVGEKAR LTIPGPYAYG PRGFPGLIPP NSTLVFDVEL LKVN 115
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0413--Isomerase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0697--Rotamase
Interpro

IPR023566--PPIase_FKBP
IPR001179--PPIase_FKBP_dom
PROSITE

PS50059--FKBP_PPIASE
Pfam

PF00254--FKBP_C
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0005528--F:FK506 binding
GO:0005527--F:macrolide binding
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0061077--P:chaperone-mediated protein folding
GO:0006325--P:chromatin organization
GO:0006457--P:protein folding
GO:0000413--P:protein peptidyl-prolyl isomerization
GO:1901710--P:regulation of homoserine biosynthetic process