| Tag |
Content |
| dbPAF ID |
dbPAF-0006590 |
| Uniprot Accession |
P19454; CSK22_YEAST; D6W2C4;
|
| Genbank Protein ID |
NP_014704.1;
|
| Genbank Nucleotide ID |
NM_001183480.1;
|
| Protein Name |
Casein kinase II subunit alpha' |
| Protein Synonyms/Alias |
|
| Gene Name |
CKA2 |
| Gene Synonyms/Alias |
YOR061W;YOR29-12; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. May play a role in cell proliferation. Required for cell viability.Functional Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. May play a role in cell proliferation. Required for cell viability. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 300 | THFITSETKLAVPEV | curated | 22817900; 19823750 |
|
Sequence
(Fasta) | MPLPPSTLNQ KSNRVYSVAR VYKNACEERP QEYWDYEQGV TIDWGKISNY EIINKIGRGK 60
YSEVFSGRCI VNNQKCVIKV LKPVKMKKIY RELKILTNLT GGPNVVGLYD IVQDADSKIP 120
ALIFEEIKNV DFRTLYPTFK LPDIQYYFTQ LLIALDYCHS MGIMHRDVKP QNVMIDPTER 180
KLRLIDWGLA EFYHPGVDYN VRVASRYHKG PELLVNLNQY DYSLDLWSVG CMLAAIVFKK 240
EPFFKGSSNP DQLVKIATVL GTKELLGYLG KYGLHLPSEY DNIMRDFTKK SWTHFITSET 300
KLAVPEVVDL IDNLLRYDHQ ERLTAKEAMD HKFFKTKFE
Fasta Sequence
>P19454|CKA2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MPLPPSTLNQKSNRVYSVARVYKNACEERPQEYWDYEQGVTIDWGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFFKTKFE
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
|
| Interpro |
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF00069--Pkinase
|
| Gene Ontology |
GO:0005956--C:protein kinase CK2 complex
GO:0034456--C:UTP-C complex
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0071470--P:cellular response to osmotic stress
GO:0001300--P:chronological cell aging
GO:0007535--P:donor selection
GO:0006468--P:protein phosphorylation
GO:0006356--P:regulation of transcription from RNA polymerase I promoter
GO:0006359--P:regulation of transcription from RNA polymerase III promoter
|
