| Tag |
Content |
| dbPAF ID |
dbPAF-0006578 |
| Uniprot Accession |
P19358; METK2_YEAST; D6VTC4; E9P927;
|
| Genbank Protein ID |
NP_010790.3;
|
| Genbank Nucleotide ID |
NM_001180810.3;
|
| Protein Name |
S-adenosylmethionine synthase 2 |
| Protein Synonyms/Alias |
|
| Gene Name |
SAM2 |
| Gene Synonyms/Alias |
ETH2;YDR502C;D9719.8; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.Functional Description
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MSKSKTFLFT SESVGEGHPD KICDQVSDAI LDACLEQDPF SKVACETAAK TGMIMVFGEI 60
TTKARLDYQQ IVRDTIKKIG YDDSAKGFDY KTCNVLVAIE QQSPDIAQGL HYEKSLEDLG 120
AGDQGIMFGY ATDETPEGLP LTILLAHKLN MAMADARRDG SLPWLRPDTK TQVTVEYEDD 180
NGRWVPKRID TVVISAQHAD EISTADLRTQ LQKDIVEKVI PKDMLDENTK YFIQPSGRFV 240
IGGPQGDAGL TGRKIIVDAY GGASSVGGGA FSGKDYSKVD RSAAYAARWV AKSLVAAGLC 300
KRVQVQFSYA IGIAEPLSLH VDTYGTATKS DDEIIEIIKK NFDLRPGVLV KELDLARPIY 360
LPTASYGHFT NQEYSWEKPK KLEF
385Fasta Sequence
>P19358|SAM2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGLHYEKSLEDLGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDNGRWVPKRIDTVVISAQHADEISTADLRTQLQKDIVEKVIPKDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDDEIIEIIKKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYSWEKPKKLEF
|
| Keyword |
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0170--Cobalt
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0554--One-carbon metabolism
KW-0630--Potassium
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
|
| Interpro |
IPR022631--ADOMET_SYNTHASE_CS
IPR022630--S-AdoMet_synt_C
IPR022629--S-AdoMet_synt_central
IPR022628--S-AdoMet_synt_N
IPR002133--S-AdoMet_synthetase
IPR022636--S-AdoMet_synthetase_sfam
|
| PROSITE |
PS00376--ADOMET_SYNTHASE_1
PS00377--ADOMET_SYNTHASE_2
|
| Pfam |
PF02773--S-AdoMet_synt_C
PF02772--S-AdoMet_synt_M
PF00438--S-AdoMet_synt_N
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004478--F:methionine adenosyltransferase activity
GO:0006555--P:methionine metabolic process
GO:0006730--P:one-carbon metabolic process
GO:0006556--P:S-adenosylmethionine biosynthetic process
|
