dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006552
Uniprot Accession P19145; GAP1_YEAST; D6VXA2;
Genbank Protein ID NP_012965.3;
Genbank Nucleotide ID NM_001179829.3;
Protein Name General amino-acid permease GAP1
Protein Synonyms/Alias
Gene Name GAP1
Gene Synonyms/Alias YKR039W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Permease for various amino acids as well as for GABA. Can also transport L-cysteine and beta-alanine.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
72IEVDPNLSEAEKVAIcurated22817900; 24961812
Sequence
(Fasta)
MSNTSSYEKN NPDNLKHNGI TIDSEFLTQE PITIPSNGSA VSIDETGSGS KWQDFKDSFK 60
RVKPIEVDPN LSEAEKVAII TAQTPLKHHL KNRHLQMIAI GGAIGTGLLV GSGTALRTGG 120
PASLLIGWGS TGTMIYAMVM ALGELAVIFP ISGGFTTYAT RFIDESFGYA NNFNYMLQWL 180
VVLPLEIVSA SITVNFWGTD PKYRDGFVAL FWLAIVIINM FGVKGYGEAE FVFSFIKVIT 240
VVGFIILGII LNCGGGPTGG YIGGKYWHDP GAFAGDTPGA KFKGVCSVFV TAAFSFAGSE 300
LVGLAASESV EPRKSVPKAA KQVFWRITLF YILSLLMIGL LVPYNDKSLI GASSVDAAAS 360
PFVIAIKTHG IKGLPSVVNV VILIAVLSVG NSAIYACSRT MVALAEQRFL PEIFSYVDRK 420
GRPLVGIAVT SAFGLIAFVA ASKKEGEVFN WLLALSGLSS LFTWGGICIC HIRFRKALAA 480
QGRGLDELSF KSPTGVWGSY WGLFMVIIMF IAQFYVAVFP VGDSPSAEGF FEAYLSFPLV 540
MVMYIGHKIY KRNWKLFIPA EKMDIDTGRR EVDLDLLKQE IAEEKAIMAT KPRWYRIWNF 600
WC 603
Keyword

KW-0029--Amino-acid transport
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0832--Ubl conjugation

Interpro

IPR004841--AA-permease/SLC12A_dom
IPR002293--AA/rel_permease1
IPR004762--Amino_acid_permease_fungi
IPR004840--Amoino_acid_permease_CS

PROSITE

PS00218--AMINO_ACID_PERMEASE_1

Pfam

PF00324--AA_permease

Gene Ontology

GO:0005768--C:endosome
GO:0030134--C:ER to Golgi transport vesicle
GO:0000328--C:fungal-type vacuole lumen
GO:0005887--C:integral component of plasma membrane
GO:0005771--C:multivesicular body
GO:0005886--C:plasma membrane
GO:0005773--C:vacuole
GO:0015171--F:amino acid transmembrane transporter activity
GO:0015297--F:antiporter activity
GO:0015192--F:L-phenylalanine transmembrane transporter activity
GO:0015193--F:L-proline transmembrane transporter activity
GO:0015203--F:polyamine transmembrane transporter activity
GO:0003333--P:amino acid transmembrane transport
GO:0006865--P:amino acid transport
GO:0015823--P:phenylalanine transport
GO:1902047--P:polyamine transmembrane transport
GO:0015846--P:polyamine transport
GO:0035524--P:proline transmembrane transport