dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006522
Uniprot Accession P18900; COQ1_YEAST; D6VQ04;
Genbank Protein ID NP_009557.1;
Genbank Nucleotide ID NM_001178351.1;
Protein Name Hexaprenyl pyrophosphate synthase, mitochondrial
Protein Synonyms/Alias
Gene Name COQ1
Gene Synonyms/Alias YBR003W;YBR0109;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Assembly of polyisoprenoid side chains. The polyprenyl synthase of coenzyme Q biosynthesis catalyzes the formation from isopentenyl diphosphate of all trans-polyprenyl pyrophosphates generally ranging in length of between 6 and 10 isoprene units depending on the species.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
23SRRCRFKSSFAVALNcurated19823750
263FMQLKNTSIDADIDTcurated22817900; 20377248; 19547744
Sequence
(Fasta)		MFQRSGAAHH IKLISSRRCR FKSSFAVALN AASKLVTPKI LWNNPISLVS KEMNTLAKNI 60
VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE IPMTERNHLK IDKSDVPEDP 120
IYSKPSQNQL FQRPASSISP LHILHGIKPL NPLTKGPEPL PEETFDKQRG ILPKQRRLAE 180
IVEMIHTASL LHDDVIDHSD TRRGRPSGNA AFTNKMAVLA GDFLLGRATV SISRLHNPEV 240
VELMSNSIAN LVEGEFMQLK NTSIDADIDT IENGHKLLPV PSKKLEVKEH DFRVPSRQQG 300
LQLSHDQIIE TAFEYYIHKT YLKTAALISK SCRCAAILSG ASPAVIDECY DFGRNLGICF 360
QLVDDMLDFT VSGKDLGKPS GADLKLGIAT APVLFAWKED PSLGPLISRN FSERGDVEKT 420
IDSVRLHNGI AKTKILAEEY RDKALQNLRD SLPESDARSA LEFLTNSILT RRK 474
Keyword

KW-0181--Complete proteome
KW-0414--Isoprene biosynthesis
KW-0460--Magnesium
KW-0472--Membrane
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-1185--Reference proteome
KW-0808--Transferase
KW-0809--Transit peptide
Interpro

IPR008949--Isoprenoid_synthase_dom
IPR000092--Polyprenyl_synt
IPR017446--Polyprenyl_synth-rel
PROSITE

PS00723--POLYPRENYL_SYNTHASE_1
PS00444--POLYPRENYL_SYNTHASE_2
Pfam

PF00348--polyprenyl_synt
Gene Ontology

GO:0031314--C:extrinsic component of mitochondrial inner membrane
GO:0005739--C:mitochondrion
GO:0046872--F:metal ion binding
GO:0000010--F:trans-hexaprenyltranstransferase activity
GO:0008299--P:isoprenoid biosynthetic process
GO:0006744--P:ubiquinone biosynthetic process