dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006520
Uniprot Accession P18888; SNF6_YEAST; D3DKU3;
Genbank Protein ID NP_011838.1;
Genbank Nucleotide ID NM_001179105.1;
Protein Name Transcription regulatory protein SNF6
Protein Synonyms/Alias SWI/SNF complex component SNF6;
Gene Name SNF6
Gene Synonyms/Alias YHL025W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
122NDAFNMLSLTTVPCDcurated25704821
125FNMLSLTTVPCDRIEcurated25704821
165ELQEKPLTPLKYTKLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900;
283QVVTTVASQSPHATAcurated25315811
285VTTVASQSPHATATEcurated20377248
Sequence
(Fasta)
MGVIKKKRSH HGKASRQQYY SGVQVGGVGS MGAINNNIPS LTSFAEENNY QYGYSGSSAG 60
MNGRSLTYAQ QQLNKQRQDF ERVRLRPEQL SNIIHDESDT ISFRSNLLKN FISSNDAFNM 120
LSLTTVPCDR IEKSRLFSEK TIRYLMQKQH EMKTQAAELQ EKPLTPLKYT KLIAAAEDGS 180
RSTKDMIDAV FEQDSHLRYQ PDGVVVHRDD PALVGKLRGD LREAPADYWT HAYRDVLAQY 240
HEAKERIRQK EVTAGEAQDE ASLQQQQQQD LQQQQQVVTT VASQSPHATA TEKEPVPAVV 300
DDPLENMFGD YSNEPFNTNF DDEFGDLDAV FF 333
Keyword

KW-0010--Activator
KW-0024--Alternative initiation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro
PROSITE
Pfam
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0016514--C:SWI/SNF complex
GO:0006338--P:chromatin remodeling
GO:0006289--P:nucleotide-excision repair
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0005987--P:sucrose catabolic process
GO:0006351--P:transcription, DNA-templated