dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006481
Uniprot Accession P18562; UPP_YEAST; D3DL77;
Genbank Protein ID NP_011996.2;
Genbank Nucleotide ID NM_001179258.1;
Protein Name Uracil phosphoribosyltransferase
Protein Synonyms/Alias
Gene Name FUR1
Gene Synonyms/Alias YHR128W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
82MGKICGVSIVRAGESdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19366988; 22817900
114LIQRDEETALPKLFYcurated22817900
164GVKPERIYFLNLICScurated22817900
171YFLNLICSKEGIEKYcurated22817900
Sequence
(Fasta)
MSSEPFKNVY LLPQTNQLLG LYTIIRNKNT TRPDFIFYSD RIIRLLVEEG LNHLPVQKQI 60
VETDTNENFE GVSFMGKICG VSIVRAGESM EQGLRDCCRS VRIGKILIQR DEETALPKLF 120
YEKLPEDISE RYVFLLDPML ATGGSAIMAT EVLIKRGVKP ERIYFLNLIC SKEGIEKYHA 180
AFPEVRIVTG ALDRGLDENK YLVPGLGDFG DRYYCV 217
Keyword

KW-0021--Allosteric enzyme
KW-0181--Complete proteome
KW-0328--Glycosyltransferase
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR029057--PRTase-like

PROSITE
Pfam
Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0004845--F:uracil phosphoribosyltransferase activity
GO:0008655--P:pyrimidine-containing compound salvage
GO:0044206--P:UMP salvage