dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006466
Uniprot Accession P18480; SNF5_YEAST; D6VQT4;
Genbank Protein ID NP_009848.4;
Genbank Nucleotide ID NM_001178637.4;
Protein Name SWI/SNF chromatin-remodeling complex subunit SNF5
Protein Synonyms/Alias SWI/SNF complex subunit SNF5;Transcription factor TYE4;Transcription regulatory protein SNF5;
Gene Name SNF5
Gene Synonyms/Alias SWI10;TYE4;YBR289W;YBR2036;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
818GTNAMLPSPESLKTKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19823750; 19795423;
821AMLPSPESLKTKLNSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289; 22817900
851ANHTVTNSPNPTLQPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 24961812
Sequence
(Fasta)		MNNQPQGTNS VPNSIGNIFS NIGTPSFNMA QIPQQLYQSL TPQQLQMIQQ RHQQLLRSRL 60
QQQQQQQQQT SPPPQTHQSP PPPPQQSQPI ANQSATSTPP PPPAPHNLHP QIGQVPLAPA 120
PINLPPQIAQ LPLATQQQVL NKLRQQAIAK NNPQVVNAIT VAQQQVQRQI EQQKGQQTAQ 180
TQLEQQRQLL VQQQQQQQLR NQIQRQQQQQ FRHHVQIQQQ QQKQQQQQQQ HQQQQQQQQQ 240
QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQGQ IPQSQQVPQV RSMSGQPPTN VQPTIGQLPQ 300
LPKLNLPKYQ TIQYDPPETK LPYPTYWSDK KADTDTLLYE QIIQRDKINK YSLIRETNGY 360
DPFSIYGFSN KEYISRLWHT LKYYQDLKNT RMKSITSTSQ KIPSASIWGN GYSGYGNGIT 420
NTTTRVIPQV EVGNRKHYLE DKLKVYKQAM NETSEQLVPI RLEFDQDRDR FFLRDTLLWN 480
KNDKLIKIED FVDDMLRDYR FEDATREQHI DTICQSIQEQ IQEFQGNPYI ELNQDRLGGD 540
DLRIRIKLDI VVGQNQLIDQ FEWDISNSDN CPEEFAESMC QELELPGEFV TAIAHSIREQ 600
VHMYHKSLAL LGYNFDGSAI EDDDIRSRML PTITLDDVYR PAAESKIFTP NLLQISAAEL 660
ERLDKDKDRD TRRKRRQGRS NRRGMLALSG TSASNTSMNG VHNTVAAGNA SSLPPGEILL 720
PDIADIPRTF RTPVPSTLMP GGVDVGPSVE SYELRNTTTY KSRPDRPKPV SPPCYIIDHI 780
PGHSLLLSIK LPGKVNTKEE FAAAPNDTSS GTNAMLPSPE SLKTKLNSNI RAGVTIPSIP 840
NPIANHTVTN SPNPTLQPVI PGGAASKSVP TPSLPIAPPV APHDSEATLL TNSNNGSSNN 900
NTQNT 906
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR006939--SNF5
PROSITE
Pfam

PF04855--SNF5
Gene Ontology

GO:0005829--C:cytosol
GO:0000228--C:nuclear chromosome
GO:0005634--C:nucleus
GO:0016514--C:SWI/SNF complex
GO:0001102--F:RNA polymerase II activating transcription factor binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0000436--P:carbon catabolite activation of transcription from RNA polymerase II promoter
GO:0006338--P:chromatin remodeling
GO:0000724--P:double-strand break repair via homologous recombination
GO:0044772--P:mitotic cell cycle phase transition
GO:0006337--P:nucleosome disassembly
GO:2000219--P:positive regulation of invasive growth in response to glucose limitation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0005987--P:sucrose catabolic process
GO:0006351--P:transcription, DNA-templated