dbPAF Protein Information
| Tag | Content | ||||||||||||
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| dbPAF ID | dbPAF-0006401 | ||||||||||||
| Uniprot Accession | P17883; SKI3_YEAST; Q06585; | ||||||||||||
| Genbank Protein ID | NP_015515.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001184286.1; | ||||||||||||
| Protein Name | Superkiller protein 3 | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | SKI3 | ||||||||||||
| Gene Synonyms/Alias | YPR189W;P9677.7; | ||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||
| Functional Description (View all) |
Component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon. | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MSDIKQLLKE AKQELTNRDY EETIEISEKV LKLDPDNYFA HIFLGKALSS LPASNNVSSN 60 RNLERATNHY VSAAKLVPDN LLAWKGLFLL FRTTEVVPDI LSYDEYFDLC GQYADALLKQ 120 EQSQVELIND IKLLKKTHPD CQKAFYQHLK PGSLMAETIG RHLSTPQDAL LNLIKILSNI 180 ETTEIGKTLS QNRLKLKASD PDYQIKLNSF SWEIIKNSEI DQLYNQLVNI LADDQKRSEI 240 ENQWLEYRIK VLKSMPLDVK KDFFTKVKEM VEDMVLVNHQ SLLAWQKYFE WTDYEDLDNM 300 DAPLIIKYFK KFPKDPLAMI LYSWLSSKLS KYDIKSLESA NKPPEGHKKT EKETDIKDVD 360 ETNEDEVKDR VEDEVKDRVE DEVKDQDEEA KEDEEEDLDD IEIGLLEEEV VTVLTENIVK 420 CKNNILAHRI LCQYYLLTKE YEAALPYIKN GISLIAYNIK DLGVHLPLTK REFSLDLATV 480 YTYVDAPKDH NAALKLYDNI LSGDFSNIQA KMGKGIIFIE RKNWKDAMTL LTQVHEQSPN 540 NLEVLSELSW SKAHMGYMDE ALAGLDTVIK GIKGMDLRSI DFRALNLWRQ AKVYIMKHAS 600 INDAKQENVK CAFKLLIQSI KILDTFAPGF STLGDIYCHY YKDHLRAFKC YFKAFDLDAG 660 DYTAAKYITE TYASKPNWQA ASSIASRLIK GEKAKAELRS NNWPFRVVGI AHLEKQEESD 720 SIEWFQSALR VDPNDVESWV GLGQAYHACG RIEASIKVFD KAIQLRPSHT FAQYFKAISL 780 CDVGEYLESL DILEKVCQEA ATEESFQIGL VEVLMRCSLD LYSQGFLLKS VSIAKDTIER 840 IKIIISELKC ENQQVWIYLS QVLRLFIWIE SKVDTLPVES LVSIFENSQF SGSEEIDSVD 900 NIKIDTLLDS TTDDNVSIAC KFLILASKYS VSDQKFTDIA GTVRASYWYN IGISELTAFI 960 TLKEPQYRDA AIFAFKKSIQ LQSNTSETWI GLGIATMDIN FRVSQHCFIK ATALEPKATN 1020 TWFNLAMLGL KKKDTEFAQQ VLNKLQSLAP QDSSPWLGMA LILEEQGDII GSSKLFAHSF 1080 ILSNGRSKAA QFMYAKNVLE NHINNGDDER DIETVEKLTT ASIALEQFFK KSPDSQFALQ 1140 CALLTLERLH HYENANELAN RLIGILEKKF EKTQDERELF NFAIIKGQFA RIHLGLGNFE 1200 LSIENADLSQ GIISESSDEK SMKTKISNHI CLGLSYFFLN DFDQTLNQFQ ELLSISKDSK 1260 HLVVLIAKVL YDVGESDTKE IALQELTEYI ATSGADLLVT LTIAAMSILD DKREDLSIIL 1320 EELKALPLSK QIIDKHKDAP YLIEEITKRL YRNDTGKQVW QRSAYFFPNN LKVWERLDKN 1380 IQRRIASNGQ NKVTAEEMSK LYCESKNLRS IQRGMFLCPW NVTAVKALNE CF 1433 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | IPR013026--TPR-contain_dom |
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| PROSITE | |||||||||||||
| Pfam | |||||||||||||
| Gene Ontology | GO:0005634--C:nucleus |