dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006347
Uniprot Accession P17505; MDHM_YEAST; D6VXK3; E9P8U0;
Genbank Protein ID NP_012838.1;
Genbank Nucleotide ID NM_001179651.1;
Protein Name Malate dehydrogenase, mitochondrial
Protein Synonyms/Alias
Gene Name MDH1
Gene Synonyms/Alias YKL085W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
177IRAARFISEVENTDPdbPTM 3.0;PhosphoGRID 2.0;UniProt17761666; 16381945; 23193290
196VNVIGGHSGITIIPLPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 22817900
199IGGHSGITIIPLISQPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 22817900
213QTNHKLMSDDKRHELcurated22369663
306IHPIGELSSEEEEMLcurated22369663; 22817900; 19547744
333KGVNFVASK------curated22369663
Sequence
(Fasta)		MLSRVAKRAF SSTVANPYKV TVLGAGGGIG QPLSLLLKLN HKVTDLRLYD LKGAKGVATD 60
LSHIPTNSVV KGFTPEEPDG LNNALKDTDM VLIPAGVPRK PGMTRDDLFA INASIVRDLA 120
AATAESAPNA AILVISNPVN STVPIVAQVL KNKGVYNPKK LFGVTTLDSI RAARFISEVE 180
NTDPTQERVN VIGGHSGITI IPLISQTNHK LMSDDKRHEL IHRIQFGGDE VVKAKNGAGS 240
ATLSMAHAGA KFANAVLSGF KGERDVIEPS FVDSPLFKSE GIEFFASPVT LGPDGIEKIH 300
PIGELSSEEE EMLQKCKETL KKNIEKGVNF VASK 335
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0496--Mitochondrion
KW-0520--NAD
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0816--Tricarboxylic acid cycle
Interpro

IPR001557--L-lactate/malate_DH
IPR022383--Lactate/malate_DH_C
IPR001236--Lactate/malate_DH_N
IPR015955--Lactate_DH/Glyco_Ohase_4_C
IPR001252--Malate_DH_AS
IPR010097--Malate_DH_type1
IPR016040--NAD(P)-bd_dom
PROSITE

PS00068--MDH
Pfam

PF02866--Ldh_1_C
PF00056--Ldh_1_N
Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0005739--C:mitochondrion
GO:0030060--F:L-malate dehydrogenase activity
GO:0003729--F:mRNA binding
GO:0009060--P:aerobic respiration
GO:0005975--P:carbohydrate metabolic process
GO:0001300--P:chronological cell aging
GO:0006108--P:malate metabolic process
GO:0001302--P:replicative cell aging
GO:0006099--P:tricarboxylic acid cycle