dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006288
Uniprot Accession P17064; FCY2_YEAST; D3DLV9;
Genbank Protein ID NP_010976.1;
Genbank Nucleotide ID NM_001178947.1;
Protein Name Purine-cytosine permease FCY2
Protein Synonyms/Alias
Gene Name FCY2
Gene Synonyms/Alias YER056C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 This permease has a broad specificity towards purines, and also transport cytosine and 5-methylcytosine but neither uracil nor thymine.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
18IQDLEKRSPVIGSSLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated15665377; 16381945; 23193290; 20702584; 19779198; 19366988;
23KRSPVIGSSLENEKKPhosphoGRID 2.0;curated20702584; 19779198; 22817900; 25315811
24RSPVIGSSLENEKKVPhosphoGRID 2.0;curated20702584; 19779198; 22369663; 22817900; 25315811; 20377248
40ASETFTATSEDDQQYPhosphoGRID 2.020702584
Sequence
(Fasta)		MLEEGNNVYE IQDLEKRSPV IGSSLENEKK VAASETFTAT SEDDQQYIVE SSEATKLSWF 60
HKFFASLNAE TKGVEPVTED EKTDDSILNA ASMWFSANMV IASYALGALG PMVFGLNFGQ 120
SVLVIIFFNI MGLIFVAFFS VFGAELGLRQ MILSRYLVGN VTARIFSLIN VIACVGWGIV 180
NTSVSAQLLN MVNEGSGHVC PIWAGCLIII GGTVLVTFFG YSVIHAYEKW SWVPNFAVFL 240
VIIAQLSRSG KFKGGEWVGG ATTAGSVLSF GSSIFGFAAG WTTYAADYTV YMPKSTNKYK 300
IFFSLVAGLA FPLFFTMILG AASAMAALND PTWKAYYDKN AMGGVIYAIL VPNSLNGFGQ 360
FCCVLLALST IANNIPNMYT VALSAQALWA PLAKIPRVVW TMAGNAATLG ISIPATYYFD 420
GFMENFMDSI GYYLAIYIAI SCSEHFFYRR SFSAYNIDDW DNWEHLPIGI AGTAALIVGA 480
FGVALGMCQT YWVGEIGRLI GKYGGDIGFE LGASWAFIIY NILRPLELKY FGR 534
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR012681--NCS1
IPR001248--Pur-cyt_permease
IPR026030--Pur-cyt_permease_Fcy2/21/22
PROSITE
Pfam

PF02133--Transp_cyt_pur
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0015212--F:cytidine transmembrane transporter activity
GO:0015205--F:nucleobase transmembrane transporter activity
GO:0015861--P:cytidine transport
GO:0015856--P:cytosine transport
GO:0072530--P:purine-containing compound transmembrane transport