dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006233
Uniprot Accession P16620; PTP69_DROME; Q8IGY3; Q9VU03;
Genbank Protein ID NP_524048.2; NP_788502.1;
Genbank Nucleotide ID NM_079324.3; NM_176324.2;
Protein Name Tyrosine-protein phosphatase 69D
Protein Synonyms/Alias Protein-tyrosine-phosphate phosphohydrolase;DPTP;
Gene Name Ptp69D
Gene Synonyms/Alias DPTP;CG10975;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Possible cell adhesion receptor.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
1372IELVDQAYNHYKNNKcurated22817900
1375VDQAYNHYKNNKNSGcurated22817900
Sequence
(Fasta)
MALLYRRMSM LLNIILAYIF LCAICVQGSV KQEWAEIGKN VSLECASENE AVAWKLGNQT 60
INKNHTRYKI RTEPLKSNDD GSENNDSQDF IKYKNVLALL DVNIKDSGNY TCTAQTGQNH 120
STEFQVRPYL PSKVLQSTPD RIKRKIKQDV MLYCLIEMYP QNETTNRNLK WLKDGSQFEF 180
LDTFSSISKL NDTHLNFTLE FTEVYKKENG TYKCTVFDDT GLEITSKEIT LFVMEVPQVS 240
IDFAKAVGAN KIYLNWTVND GNDPIQKFFI TLQEAGTPTF TYHKDFINGS HTSYILDHFK 300
PNTTYFLRIV GKNSIGNGQP TQYPQGITTL SYDPIFIPKV ETTGSTASTI TIGWNPPPPD 360
LIDYIQYYEL IVSESGEVPK VIEEAIYQQN SRNLPYMFDK LKTATDYEFR VRACSDLTKT 420
CGPWSENVNG TTMDGVATKP TNLSIQCHHD NVTRGNSIAI NWDVPKTPNG KVVSYLIHLL 480
GNPMSTVDRE MWGPKIRRID EPHHKTLYES VSPNTNYTVT VSAITRHKKN GEPATGSCLM 540
PVSTPDAIGR TMWSKVNLDS KYVLKLYLPK ISERNGPICC YRLYLVRINN DNKELPDPEK 600
LNIATYQEVH SDNVTRSSAY IAEMISSKYF RPEIFLGDEK RFSENNDIIR DNDEICRKCL 660
EGTPFLRKPE IIHIPPQGSL SNSDSELPIL SEKDNLIKGA NLTEHALKIL ESKLRDKRNA 720
VTSDENPILS AVNPNVPLHD SSRDVFDGEI DINSNYTGFL EIIVRDRNNA LMAYSKYFDI 780
ITPATEAEPI QSLNNMDYYL SIGVKAGAVL LGVILVFIVL WVFHHKKTKN ELQGEDTLTL 840
RDSLSRALFG RRNHNHSHFI TSGNHKGFDA GPIHRLDLEN AYKNRHKDTD YGFLREYEML 900
PNRFSDRTTK NSDLKENACK NRYPDIKAYD QTRVKLAVIN GLQTTDYINA NFVIGYKERK 960
KFICAQGPME STIDDFWRMI WEQHLEIIVM LTNLEEYNKA KCAKYWPEKV FDTKQFGDIL 1020
VKFAQERKTG DYIERTLNVS KNKANVGEEE DRRQITQYHY LTWKDFMAPE HPHGIIKFIR 1080
QINSVYSLQR GPILVHCSAG VGRTGTLVAL DSLIQQLEEE DSVSIYNTVC DLRHQRNFLV 1140
QSLKQYIFLY RALLDTGTFG NTDICIDTMA SAIESLKRKP NEGKCKLEVE FEKLLATADE 1200
ISKSCSVGEN EENNMKNRSQ EIIPYDRNRV ILTPLPMREN STYINASFIE GYDNSETFII 1260
AQDPLENTIG DFWRMISEQS VTTLVMISEI GDGPRKCPRY WADDEVQYDH ILVKYVHSES 1320
CPYYTRREFY VTNCKIDDTL KVTQFQYNGW PTVDGEVPEV CRGIIELVDQ AYNHYKNNKN 1380
SGCRSPLTVH CSLGTDRSSI FVAMCILVQH LRLEKCVDIC ATTRKLRSQR TGLINSYAQY 1440
EFLHRAIINY SDLHHIAEST LD 1463
Keyword

KW-0025--Alternative splicing
KW-0130--Cell adhesion
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0378--Hydrolase
KW-0393--Immunoglobulin domain
KW-0472--Membrane
KW-0904--Protein phosphatase
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003961--FN3_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR029021--Prot-tyrosine_phosphatase-like
IPR000242--PTPase_domain
IPR016130--Tyr_Pase_AS
IPR000387--TYR_PHOSPHATASE_dom

PROSITE

PS50853--FN3
PS50835--IG_LIKE
PS00383--TYR_PHOSPHATASE_1
PS50056--TYR_PHOSPHATASE_2
PS50055--TYR_PHOSPHATASE_PTP

Pfam

PF00041--fn3
PF00102--Y_phosphatase

Gene Ontology

GO:0030424--C:axon
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0004725--F:protein tyrosine phosphatase activity
GO:0005001--F:transmembrane receptor protein tyrosine phosphatase activity
GO:0007411--P:axon guidance
GO:0007414--P:axonal defasciculation
GO:0007155--P:cell adhesion
GO:0007415--P:defasciculation of motor neuron axon
GO:0048813--P:dendrite morphogenesis
GO:0097155--P:fasciculation of sensory neuron axon
GO:0046331--P:lateral inhibition
GO:0008045--P:motor neuron axon guidance
GO:0035335--P:peptidyl-tyrosine dephosphorylation
GO:0006470--P:protein dephosphorylation