dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0006206 | ||||||||
| Uniprot Accession | P16451; ODPX_YEAST; D6VUX5; E9P906; | ||||||||
| Genbank Protein ID | NP_011709.1; | ||||||||
| Genbank Nucleotide ID | NM_001181322.1; | ||||||||
| Protein Name | Pyruvate dehydrogenase complex protein X component, mitochondrial | ||||||||
| Protein Synonyms/Alias | Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex;E3-binding protein;Pyruvate dehydrogenase complex component E3BP; | ||||||||
| Gene Name | PDX1 | ||||||||
| Gene Synonyms/Alias | YGR193C;G7579; | ||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
| NCBI Taxa ID | 559292 | ||||||||
| Functional Description (View all) |
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MLSAISKVST LKSCTRYLTK CNYHASAKLL AVKTFSMPAM SPTMEKGGIV SWKYKVGEPF 60 SAGDVILEVE TDKSQIDVEA LDDGKLAKIL KDEGSKDVDV GEPIAYIADV DDDLATIKLP 120 QEANTANAKS IEIKKPSADS TEATQQHLKK ATVTPIKTVD GSQANLEQTL LPSVSLLLAE 180 NNISKQKALK EIAPSGSNGR LLKGDVLAYL GKIPQDSVNK VTEFIKKNER LDLSNIKPIQ 240 LKPKIAEQAQ TKAADKPKIT PVEFEEQLVF HAPASIPFDK LSESLNSFMK EAYQFSHGTP 300 LMDTNSKYFD PIFEDLVTLS PREPRFKFSY DLMQIPKANN MQDTYGQEDI FDLLTGSDAT 360 ASSVRPVEKN LPEKNEYILA LNVSVNNKKF NDAEAKAKRF LDYVRELESF 411 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR003016--2-oxoA_DH_lipoyl-BS |
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| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005967--C:mitochondrial pyruvate dehydrogenase complex |