Tag |
Content |
dbPAF ID |
dbPAF-0006160 |
Uniprot Accession |
P16241; CF1A_DROME; Q24460; Q86P26; Q9VRY9; |
Genbank Protein ID |
NP_001286957.1; NP_523948.1; |
Genbank Nucleotide ID |
NM_001300028.1; NM_079224.5; |
Protein Name |
POU domain protein CF1A |
Protein Synonyms/Alias |
Chorion factor 1A;CF1-A;Protein drifter;Ventral veins lacking protein; |
Gene Name |
vvl |
Gene Synonyms/Alias |
Cf1a;CG10037; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
Binds to a DNA sequence element required for the expression of the dopa decarboxylase gene (Ddc) in specific dopaminergic neurons. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system.Functional Description
Binds to a DNA sequence element required for the expression of the dopa decarboxylase gene (Ddc) in specific dopaminergic neurons. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system.
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Phosphorylation Sites
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dbPAF PTMs: 1 |
Sequence (Fasta) | MAATSYMTPP SGDLDMALGG GGYHTSSPRS AADAGEMKYM QHHHHHHAAA AAAAHHQLPS 60 SPSPNGQGNG GGLGLGSGSG LGSWSALHPD PWMQTHHTHH LPAAAAVASA ADTVKQEMSH 120 LSQQTRIQQG MASPHAAWHA PHAGHYAPTG GSPLQYHHAM NGMLHHPAHA VAAAHHQSVA 180 PLHHTLRGES PQLHIHHHMG GGDRDAISGG EEDTPTSDDL EAFAKQFKQR RIKLGFTQAD 240 VGLALGTLYG NVFSQTTICR FEALQLSFKN MCKLKPLLQK WLEEADSTTG SPTSIDKIAA 300 QGRKRKKRTS IEVSVKGALE QHFHKQPKPS AQEITSLADS LQLEKEVVRV WFCNRRQKEK 360 RMTPPNTLGG DMMDGMPPGH MHHGGYHPHH DMHGSPMGTH SHSHSPPMLS PQNMQSSAVA 420 AHQLAAH
428Fasta Sequence
>P16241|vvl|Drosophila melanogaster(Fruit fly) MAATSYMTPPSGDLDMALGGGGYHTSSPRSAADAGEMKYMQHHHHHHAAAAAAAHHQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAAAVASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLHHPAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAH
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Keyword |
KW-0010--Activator KW-0181--Complete proteome KW-0238--DNA-binding KW-0371--Homeobox KW-0539--Nucleus KW-1185--Reference proteome KW-0804--Transcription KW-0805--Transcription regulation
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Interpro |
IPR017970--Homeobox_CS IPR001356--Homeobox_dom IPR009057--Homeodomain-like IPR010982--Lambda_DNA-bd_dom IPR013847--POU IPR000327--POU_dom IPR016362--TF_POU_3
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PROSITE |
PS00027--HOMEOBOX_1 PS50071--HOMEOBOX_2 PS00035--POU_1 PS00465--POU_2 PS51179--POU_3
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Pfam |
PF00046--Homeobox PF00157--Pou
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Gene Ontology |
GO:0005634--C:nucleus GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding GO:0003700--F:transcription factor activity, sequence-specific DNA binding GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0007420--P:brain development GO:0035284--P:brain segmentation GO:0048813--P:dendrite morphogenesis GO:0007425--P:epithelial cell fate determination, open tracheal system GO:0008045--P:motor neuron axon guidance GO:0007422--P:peripheral nervous system development GO:0002807--P:positive regulation of antimicrobial peptide biosynthetic process GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter GO:0048814--P:regulation of dendrite morphogenesis GO:0006366--P:transcription from RNA polymerase II promoter
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