dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006145
Uniprot Accession P16120; THRC_YEAST; D6VR61; E9P943;
Genbank Protein ID NP_009982.1;
Genbank Nucleotide ID NM_001178767.1;
Protein Name Threonine synthase
Protein Synonyms/Alias
Gene Name THR4
Gene Synonyms/Alias YCR053W;YCR53W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
5---MPNASQVYRSTRcurated22369663
104TPLVQNVTGDKENLHPhosphoGRID 2.0;curated19779198; 22369663; 22817900; 19823750; 24961812; 25315811;
408SETIKKIYESSVNPKcurated19823750
410TIKKIYESSVNPKHYPhosphoGRID 2.0;curated21126336; 19823750
441IAKDNDKSIQYISLSPhosphoPep 2.019060867
464DAVNNALSGFSNYSFcurated26040406
467NNALSGFSNYSFEKDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 26040406; 22369663;
469ALSGFSNYSFEKDVLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
470LSGFSNYSFEKDVLPdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040406
Sequence
(Fasta)		MPNASQVYRS TRSSSPKTIS FEEAIIQGLA TDGGLFIPPT IPQVDQATLF NDWSKLSFQD 60
LAFAIMRLYI AQEEIPDADL KDLIKRSYST FRSDEVTPLV QNVTGDKENL HILELFHGPT 120
YAFKDVALQF VGNLFEYFLQ RTNANLPEGE KKQITVVGAT SGDTGSAAIY GLRGKKDVSV 180
FILYPTGRIS PIQEEQMTTV PDENVQTLSV TGTFDNCQDI VKAIFGDKEF NSKHNVGAVN 240
SINWARILAQ MTYYFYSFFQ ATNGKDSKKV KFVVPSGNFG DILAGYFAKK MGLPIEKLAI 300
ATNENDILDR FLKSGLYERS DKVAATLSPA MDILISSNFE RLLWYLAREY LANGDDLKAG 360
EIVNNWFQEL KTNGKFQVDK SIIEGASKDF TSERVSNEET SETIKKIYES SVNPKHYILD 420
PHTAVGVCAT ERLIAKDNDK SIQYISLSTA HPAKFADAVN NALSGFSNYS FEKDVLPEEL 480
KKLSTLKKKL KFIERADVEL VKNAIEEELA KMKL 515
Keyword

KW-0002--3D-structure
KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0456--Lyase
KW-0597--Phosphoprotein
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0791--Threonine biosynthesis
Interpro

IPR000634--Ser/Thr_deHydtase_PyrdxlP-BS
IPR029144--Thr_synth_N
IPR004450--Thr_synthase-like
IPR001926--TrpB-like_PLP-dep
PROSITE

PS00165--DEHYDRATASE_SER_THR
Pfam

PF00291--PALP
PF14821--Thr_synth_N
Gene Ontology

GO:0030170--F:pyridoxal phosphate binding
GO:0004795--F:threonine synthase activity
GO:0009088--P:threonine biosynthetic process