dbPAF Protein Information
Tag | Content | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dbPAF ID | dbPAF-0006115 | ||||||||||||||||
Uniprot Accession | P15938; PRP16_YEAST; D6VXE6; | ||||||||||||||||
Genbank Protein ID | NP_013012.3; | ||||||||||||||||
Genbank Nucleotide ID | NM_001179876.3; | ||||||||||||||||
Protein Name | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 | ||||||||||||||||
Protein Synonyms/Alias | |||||||||||||||||
Gene Name | PRP16 | ||||||||||||||||
Gene Synonyms/Alias | YKR086W;YKR406; | ||||||||||||||||
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||||||
NCBI Taxa ID | 559292 | ||||||||||||||||
Functional Description (View all) |
Influences the fidelity of branchpoint recognition in yeast splicing. This is RNA-dependent ATPase which is essential for viability. It may mediate one of the many ATP-requiring steps of spliceosome assembly and that accuracy of branchpoint recognition may be coupled to ATP binding and/or hydrolysis. | ||||||||||||||||
Phosphorylation Sites |
dbPAF PTMs: 3
|
||||||||||||||||
Sequence (Fasta) | MGHSGREERI KDIFKELTSK ELTPGLLLTL QKLAQKPNTN LEQFIASCKA LTKLSSNNPI 60 IFNELLELLK NKSEEDSTGP KKIAPSINKR KKFKIQLDLD DNEDELDSPV QKKPAPTRTL 120 FKRIDKLKAK QLRQYSPTVK DPSPNSEQQT QNGHAETKDY EPTRSEVVEE DREWYDNDDD 180 YGNLVPEPLS ELPEEAKLLP VIRNIDNDDA LRNTVQLYPI PLKQRMEWIP PFLSKFALEN 240 KVPTSIIIGS ISETSSQVSA LSMVNPFRNP DSEFSANAKR GSKLVALRRI NMEHIQQSRD 300 NTTVLNTAMG EVLGLENNNK AKDKSNQKIC DDTALFTPSK DDIKHTKEQL PVFRCRSQLL 360 SLIRENQVVV IIGETGSGKT TQLAQYLYEE GYANDRGKSI VVTQPRRVAA ISVAKRVAME 420 MQVPLGKEVG YSIRFEDVTD SECTKLKFVT DGILLRETLL DDTLDKYSCV IIDEAHERSL 480 NTDILLGFFK ILLARRRDLK LIITSATMNA KKFSAFFGNA PQFTIPGRTF PVQTIYTSNP 540 VQDYVEAAVS QAVKIHLAND CSSGDILIFM TGQEDIETTF DTLQEKFLQV YSKKFGTANF 600 EEINDIEILP IYSALPADLQ FKIFQDLHGT KRKIIIATNI AETSLTIKGI RYVIDCGYSK 660 LKVYNPKIGL DSLVITPISK ANADQRSGRA GRTAPGTAYR LYTEDTFKED MYLQTIPEIQ 720 RTNLSNTLLL LKSLDVTDEL SKFPFIDKPP LQTFLSSLYE LWFIGAIDTS GQLTPLGLQM 780 AKFPLQPSLS KILLIAVRNG CSDEMLTIVS MLSVPQVFYR PKERQKEADI ARNKFFIAKS 840 DHLTLLNVFE QWRANNFSSH WCNKHFVQYK SLVRARDIRD QLLTILKSQK IPVISSGKDW 900 DIIKKCICSG FAHQAAKITG LRNYVHLKTG VSVQLHPTSA LHGLGDLPPY VVYHELLMTS 960 KEYICCVTSV DPFWLMEYGG LLYDIKRIKN DQEATTTGLF GEHYEHTLDK VEDDIDINIR 1020 RCKDMRDSVI QELKMTDNSN KEDKKQKTKK QNILNGKENS MKPFKRRKPF F 1072 |
||||||||||||||||
Keyword | KW-0067--ATP-binding |
||||||||||||||||
Interpro | IPR011545--DEAD/DEAH_box_helicase_dom |
||||||||||||||||
PROSITE | PS00690--DEAH_ATP_HELICASE |
||||||||||||||||
Pfam | PF00270--DEAD |
||||||||||||||||
Gene Ontology | GO:0005737--C:cytoplasm |