dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006091
Uniprot Accession P15801; DPOG_YEAST; D6W327; Q08785;
Genbank Protein ID NP_014975.2;
Genbank Nucleotide ID NM_001183750.1;
Protein Name DNA polymerase gamma
Protein Synonyms/Alias Mitochondrial DNA polymerase catalytic subunit;
Gene Name MIP1
Gene Synonyms/Alias YOR330C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in the replication of mitochondrial DNA.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
791ANKLYENTKGKTKRSPhosphoGRID 2.0;curated21177495; 22817900
795YENTKGKTKRSKLFKPhosphoGRID 2.0;curated21177495; 22817900
Sequence
(Fasta)		MTKLMVRSEC MLRMVRRRPL RVQFCARWFS TKKNTAEAPR INPVGIQYLG ESLQRQVFGS 60
CGGKDEVEQS DKLMELSKKS LKDHGLWGKK TLITDPISFP LPPLQGRSLD EHFQKIGRFN 120
SEPYKSFCED KFTEMVARPA EWLRKPGWVK YVPGMAPVEV AYPDEELVVF DVETLYNVSD 180
YPTLATALSS TAWYLWCSPF ICGGDDPAAL IPLNTLNKEQ VIIGHNVAYD RARVLEEYNF 240
RDSKAFFLDT QSLHIASFGL CSRQRPMFMK NNKKKEAEVE SEVHPEISIE DYDDPWLNVS 300
ALNSLKDVAK FHCKIDLDKT DRDFFASTDK STIIENFQKL VNYCATDVTA TSQVFDEIFP 360
VFLKKCPHPV SFAGLKSLSK CILPTKLNDW NDYLNSSESL YQQSKVQIES KIVQIIKDIV 420
LLKDKPDFYL KDPWLSQLDW TTKPLRLTKK GVPAKCQKLP GFPEWYRQLF PSKDTVEPKI 480
TIKSRIIPIL FKLSWENSPV IWSKESGWCF NVPHEQVETY KAKNYVLADS VSQEEEEIRT 540
HNLGLQCTGV LFKVPHPNGP TFNCTNLLTK SYNHFFEKGV LKSESELAHQ ALQINSSGSY 600
WMSARERIQS QFVVPSCKFP NEFQSLSAKS SLNNEKTNDL AIIIPKIVPM GTITRRAVEN 660
AWLTASNAKA NRIGSELKTQ VKAPPGYCFV GADVDSEELW IASLVGDSIF NVHGGTAIGW 720
MCLEGTKNEG TDLHTKTAQI LGCSRNEAKI FNYGRIYGAG AKFASQLLKR FNPSLTDEET 780
KKIANKLYEN TKGKTKRSKL FKKFWYGGSE SILFNKLESI AEQETPKTPV LGCGITYSLM 840
KKNLRANSFL PSRINWAIQS SGVDYLHLLC CSMEYIIKKY NLEARLCISI HDEIRFLVSE 900
KDKYRAAMAL QISNIWTRAM FCQQMGINEL PQNCAFFSQV DIDSVIRKEV NMDCITPSNK 960
TAIPHGEALD INQLLDKSNS KLGKPNLDID SKVSQYAYNY REPVFEEYNK SYTPEFLKYF 1020
LAMQVQSDKR DVNRLEDEYL RECTSKEYAR DGNTAEYSLL DYIKDVEKGK RTKVRIMGSN 1080
FLDGTKNAKA DQRIRLPVNM PDYPTLHKIA NDSAIPEKQL LENRRKKENR IDDENKKKLT 1140
RKKNTTPMER KYKRVYGGRK AFEAFYECAN KPLDYTLETE KQFFNIPIDG VIDDVLNDKS 1200
NYKKKPSQAR TASSSPIRKT AKAVHSKKLP ARKSSTTNRN LVELERDITI SREY 1255
Keyword

KW-0181--Complete proteome
KW-0235--DNA replication
KW-0238--DNA-binding
KW-0239--DNA-directed DNA polymerase
KW-0460--Magnesium
KW-0496--Mitochondrion
KW-0548--Nucleotidyltransferase
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR019760--DNA-dir_DNA_pol_A_CS
IPR002297--DNA-dir_DNA_pol_A_mt
IPR001098--DNA-dir_DNA_pol_A_palm_dom
IPR012337--RNaseH-like_dom
PROSITE

PS00447--DNA_POLYMERASE_A
Pfam

PF00476--DNA_pol_A
Gene Ontology

GO:0005760--C:gamma DNA polymerase complex
GO:0005739--C:mitochondrion
GO:0008408--F:3'-5' exonuclease activity
GO:0003677--F:DNA binding
GO:0003887--F:DNA-directed DNA polymerase activity
GO:0071897--P:DNA biosynthetic process
GO:0006264--P:mitochondrial DNA replication
GO:0090305--P:nucleic acid phosphodiester bond hydrolysis