| Tag |
Content |
| dbPAF ID |
dbPAF-0006088 |
| Uniprot Accession |
P15731; UBC4_YEAST; D6VQ81;
|
| Genbank Protein ID |
NP_009638.1;
|
| Genbank Nucleotide ID |
NM_001178430.1;
|
| Protein Name |
Ubiquitin-conjugating enzyme E2 4 |
| Protein Synonyms/Alias |
E2 ubiquitin-conjugating enzyme 4;Ubiquitin carrier protein 4;Ubiquitin-protein ligase 4; |
| Gene Name |
UBC4 |
| Gene Synonyms/Alias |
YBR082C;YBR0745; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Mediates ubiquitination of PEX5.Functional Description
Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Mediates ubiquitination of PEX5. |
Phosphorylation Sites
|
dbPAF PTMs: 1 |
Sequence
(Fasta) | MSSSKRIAKE LSDLERDPPT SCSAGPVGDD LYHWQASIMG PADSPYAGGV FFLSIHFPTD 60
YPFKPPKISF TTKIYHPNIN ANGNICLDIL KDQWSPALTL SKVLLSICSL LTDANPDDPL 120
VPEIAHIYKT DRPKYEATAR EWTKKYAV
149Fasta Sequence
>P15731|UBC4|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV
|
| Keyword |
KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0346--Stress response
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
|
| Interpro |
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD
|
| PROSITE |
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2
|
| Pfam |
PF00179--UQ_con
|
| Gene Ontology |
GO:0000502--C:proteasome complex
GO:0005524--F:ATP binding
GO:0030674--F:protein binding, bridging
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034605--P:cellular response to heat
GO:0071629--P:cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
