dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006086
Uniprot Accession P15705; STI1_YEAST; D6W293;
Genbank Protein ID NP_014670.1;
Genbank Nucleotide ID NM_001183446.1;
Protein Name Heat shock protein STI1
Protein Synonyms/Alias
Gene Name STI1
Gene Synonyms/Alias YOR027W;OR26.17;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 May play a role in mediating the heat shock response of some HSP70 genes. It is required for optimal growth of yeast cells at both low and high temperature.
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
2------MSLTADEYKdbPTM 3.018407956; 16381945; 23193290
37KAIEVSETPNHVLYScurated22369663
227KKDAEPQSDSTTSKEdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 21126336;
229DAEPQSDSTTSKENScurated25315811
230AEPQSDSTTSKENSScurated22817900
231EPQSDSTTSKENSSKcurated22817900; 25315811
232PQSDSTTSKENSSKAcurated22817900; 25315811
248QKEESKESEPMEVDEPhosphoGRID 2.0;curated21126336; 25315811
258MEVDEDDSKIEADKEcurated22369663
355KLGDLKKTIEYYQKScurated25315811
410GKEYFTKSDWPNAVKcurated22369663
501DAEVNNGSSAREIDQcurated25315811
522QQRFQPGTSNETPEEPhosphoGRID 2.021126336
523QRFQPGTSNETPEETdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
526QPGTSNETPEETYQRcurated22369663
Sequence
(Fasta)		MSLTADEYKQ QGNAAFTAKD YDKAIELFTK AIEVSETPNH VLYSNRSACY TSLKKFSDAL 60
NDANECVKIN PSWSKGYNRL GAAHLGLGDL DEAESNYKKA LELDASNKAA KEGLDQVHRT 120
QQARQAQPDL GLTQLFADPN LIENLKKNPK TSEMMKDPQL VAKLIGYKQN PQAIGQDLFT 180
DPRLMTIMAT LMGVDLNMDD INQSNSMPKE PETSKSTEQK KDAEPQSDST TSKENSSKAP 240
QKEESKESEP MEVDEDDSKI EADKEKAEGN KFYKARQFDE AIEHYNKAWE LHKDITYLNN 300
RAAAEYEKGE YETAISTLND AVEQGREMRA DYKVISKSFA RIGNAYHKLG DLKKTIEYYQ 360
KSLTEHRTAD ILTKLRNAEK ELKKAEAEAY VNPEKAEEAR LEGKEYFTKS DWPNAVKAYT 420
EMIKRAPEDA RGYSNRAAAL AKLMSFPEAI ADCNKAIEKD PNFVRAYIRK ATAQIAVKEY 480
ASALETLDAA RTKDAEVNNG SSAREIDQLY YKASQQRFQP GTSNETPEET YQRAMKDPEV 540
AAIMQDPVMQ SILQQAQQNP AALQEHMKNP EVFKKIQTLI AAGIIRTGR
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0325--Glycoprotein
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0346--Stress response
KW-0802--TPR repeat
Interpro

IPR006636--STI1_HS-bd
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat
PROSITE

PS50005--TPR
PS50293--TPR_REGION
Pfam

PF00515--TPR_1
PF13414--TPR_11
Gene Ontology

GO:0005737--C:cytoplasm
GO:0042030--F:ATPase inhibitor activity
GO:0030544--F:Hsp70 protein binding
GO:0051879--F:Hsp90 protein binding
GO:0003729--F:mRNA binding
GO:0043086--P:negative regulation of catalytic activity
GO:0006457--P:protein folding
GO:0008104--P:protein localization