dbPAF Protein Information
Tag | Content | ||||||||
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dbPAF ID | dbPAF-0006084 | ||||||||
Uniprot Accession | P15700; KCY_YEAST; D6VXR0; | ||||||||
Genbank Protein ID | NP_012901.3; | ||||||||
Genbank Nucleotide ID | NM_001179590.3; | ||||||||
Protein Name | Uridylate kinase | ||||||||
Protein Synonyms/Alias | |||||||||
Gene Name | URA6 | ||||||||
Gene Synonyms/Alias | SOC8;YKL024C; | ||||||||
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
NCBI Taxa ID | 559292 | ||||||||
Functional Description (View all) |
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP, AMP, GMP, dGMP and dTMP. ATP and dATP are the best phosphate donors, but can also use GTP, dGTP, dCTP, and dTTP to some degree. | ||||||||
Phosphorylation Sites |
dbPAF PTMs: 1
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Sequence (Fasta) | MTAATTSQPA FSPDQVSVIF VLGGPGAGKG TQCEKLVKDY SFVHLSAGDL LRAEQGRAGS 60 QYGELIKNCI KEGQIVPQEI TLALLRNAIS DNVKANKHKF LIDGFPRKMD QAISFERDIV 120 ESKFILFFDC PEDIMLERLL ERGKTSGRSD DNIESIKKRF NTFKETSMPV IEYFETKSKV 180 VRVRCDRSVE DVYKDVQDAI RDSL 205 |
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Keyword | KW-0002--3D-structure |
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Interpro | IPR000850--Adenylat/UMP-CMP_kin |
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PROSITE | PS00113--ADENYLATE_KINASE |
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Pfam | |||||||||
Gene Ontology | GO:0005737--C:cytoplasm |