dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006077
Uniprot Accession P15625; SYFA_YEAST; D6VTK8;
Genbank Protein ID NP_116631.1;
Genbank Nucleotide ID NM_001179944.2;
Protein Name Phenylalanine--tRNA ligase alpha subunit
Protein Synonyms/Alias Phenylalanyl-tRNA synthetase alpha subunit;PheRS;
Gene Name FRS2
Gene Synonyms/Alias YFL022C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
39DVLSALNSLKAHNKLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
117GWIAKNASNELELSAdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900;
149LAQIKNNSHLDSIDAcurated22817900
201DLTSDMVSTNAYKDLcurated24961812
202LTSDMVSTNAYKDLKcurated22817900
217FKPYNFNSQGVQISSPhosphoPep 2.019060867
311HEQGRFGSIGYRYNWPhosphoGRID 2.0;curated21126336; 19779198; 22817900
336RTHSTAISARMLHDLcurated25315811
447FRPEMLESMGLPKDLcurated19823750
Sequence
(Fasta)
MSDFQLEILK KLDELDEIKS TLATFPQHGS QDVLSALNSL KAHNKLEFSK VDTVTYDLTK 60
EGAQILNEGS YEIKLVKLIQ ELGQLQIKDV MSKLGPQVGK VGQARAFKNG WIAKNASNEL 120
ELSAKLQNTD LNELTDETQS ILAQIKNNSH LDSIDAKILN DLKKRKLIAQ GKITDFNVTK 180
GPEFSTDLTK LETDLTSDMV STNAYKDLKF KPYNFNSQGV QISSGALHPL NKVREEFRQI 240
FFSMGFTEMP SNQYVETGFW NFDALYVPQQ HPARDLQDTF YIKDPLTADL PDDKTYMDNI 300
KAVHEQGRFG SIGYRYNWKP EECQKLVLRT HSTAISARML HDLAKDPKPT RLFSIDRVFR 360
NEAVDATHLA EFHQVEGVLA DYNITLGDLI KFMEEFFERM GVTGLRFKPT YNPYTEPSME 420
IFSWHEGLQK WVEIGNSGMF RPEMLESMGL PKDLRVLGWG LSLERPTMIK YKVQNIRELL 480
GHKVSLDFIE TNPAARLDED LYE 504
Keyword

KW-0007--Acetylation
KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0648--Protein biosynthesis
KW-1185--Reference proteome

Interpro

IPR006195--aa-tRNA-synth_II
IPR004529--Phe-tRNA-synth_IIc_asu
IPR002319--Phenylalanyl-tRNA_Synthase

PROSITE

PS50862--AA_TRNA_LIGASE_II

Pfam

PF01409--tRNA-synt_2d

Gene Ontology

GO:0009328--C:phenylalanine-tRNA ligase complex
GO:0005524--F:ATP binding
GO:0004826--F:phenylalanine-tRNA ligase activity
GO:0000049--F:tRNA binding
GO:0006432--P:phenylalanyl-tRNA aminoacylation