dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0006070 |
| Uniprot Accession | P15565; TRM1_YEAST; D6VSA6; Q9URQ7; Q9URQ8; |
| Genbank Protein ID | NP_010405.3; |
| Genbank Nucleotide ID | NM_001180428.3; |
| Protein Name | tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial |
| Protein Synonyms/Alias | tRNA 2,2-dimethylguanosine-26 methyltransferase;tRNA(guanine-26,N(2)-N(2)) methyltransferase;tRNA(m(2,2)G26)dimethyltransferase; |
| Gene Name | TRM1 |
| Gene Synonyms/Alias | YDR120C;YD9727.15C; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. Required for the modification of both mitochondrial and cytoplasmic tRNAs. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MEGFFRIPLK RANLHGMLKA AISKIKANFT AYGAPRINIE DFNIVKEGKA EILFPKKETV 60 FYNPIQQFNR DLSVTCIKAW DNLYGEECGQ KRNNKKSKKK RCAETNDDSS KRQKMGNGSP 120 KEAVGNSNRN EPYINILEAL SATGLRAIRY AHEIPHVREV IANDLLPEAV ESIKRNVEYN 180 SVENIVKPNL DDANVLMYRN KATNNKFHVI DLDPYGTVTP FVDAAIQSIE EGGLMLVTCT 240 DLSVLAGNGY PEKCFALYGG ANMVSHESTH ESALRLVLNL LKQTAAKYKK TVEPLLSLSI 300 DFYVRVFVKV KTSPIEVKNV MSSTMTTYHC SRCGSYHNQP LGRISQREGR NNKTFTKYSV 360 AQGPPVDTKC KFCEGTYHLA GPMYAGPLHN KEFIEEVLRI NKEEHRDQDD TYGTRKRIEG 420 MLSLAKNELS DSPFYFSPNH IASVIKLQVP PLKKVVAGLG SLGFECSLTH AQPSSLKTNA 480 PWDAIWYVMQ KCDDEKKDLS KMNPNTTGYK ILSAMPGWLS GTVKSEYDSK LSFAPNEQSG 540 NIEKLRKLKI VRYQENPTKN WGPKARPNTS 571 |
| Keyword | KW-0007--Acetylation |
| Interpro | |
| PROSITE | PS51626--SAM_MT_TRM1 |
| Pfam | PF02005--TRM |
| Gene Ontology | GO:0005739--C:mitochondrion |