dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0006055
Uniprot Accession P15496; IDI1_YEAST; D6W3Q1;
Genbank Protein ID NP_015208.1;
Genbank Nucleotide ID NM_001183931.1;
Protein Name Isopentenyl-diphosphate Delta-isomerase
Protein Synonyms/Alias Isopentenyl pyrophosphate isomerase;IPP isomerase;
Gene Name IDI1
Gene Synonyms/Alias BOT2;YPL117C;LPH10C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
7-MTADNNSMPHGAVSdbPTM 3.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22369663; 24961812
24AKLVQNQTPEDILEEdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 22817900
46QQRPNTRSSETSNDEPhosphoGRID 2.019779198
49PNTRSSETSNDESGEcurated22817900; 25315811
50NTRSSETSNDESGETdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
57SNDESGETCFSGHDEcurated25315811
60ESGETCFSGHDEEQIcurated22817900; 25315811
Sequence
(Fasta)
MTADNNSMPH GAVSSYAKLV QNQTPEDILE EFPEIIPLQQ RPNTRSSETS NDESGETCFS 60
GHDEEQIKLM NENCIVLDWD DNAIGAGTKK VCHLMENIEK GLLHRAFSVF IFNEQGELLL 120
QQRATEKITF PDLWTNTCCS HPLCIDDELG LKGKLDDKIK GAITAAVRKL DHELGIPEDE 180
TKTRGKFHFL NRIHYMAPSN EPWGEHEIDY ILFYKINAKE NLTVNPNVNE VRDFKWVSPN 240
DLKTMFADPS YKFTPWFKII CENYLFNWWE QLDDLSEVEN DRQIHRML 289
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0413--Isomerase
KW-0414--Isoprene biosynthesis
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0752--Steroid biosynthesis
KW-0753--Steroid metabolism
KW-0756--Sterol biosynthesis
KW-1207--Sterol metabolism

Interpro

IPR011876--IsopentenylPP_isomerase_typ1
IPR000086--NUDIX_hydrolase_dom
IPR015797--NUDIX_hydrolase_dom-like

PROSITE

PS51462--NUDIX

Pfam

PF00293--NUDIX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016787--F:hydrolase activity
GO:0004452--F:isopentenyl-diphosphate delta-isomerase activity
GO:0046872--F:metal ion binding
GO:0050992--P:dimethylallyl diphosphate biosynthetic process
GO:0045337--P:farnesyl diphosphate biosynthetic process
GO:0016126--P:sterol biosynthetic process