dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006054
Uniprot Accession P15454; KGUA_YEAST; D6VT79;
Genbank Protein ID NP_010742.1;
Genbank Nucleotide ID NM_001180762.1;
Protein Name Guanylate kinase
Protein Synonyms/Alias GMP kinase;
Gene Name GUK1
Gene Synonyms/Alias YDR454C;D9461.39;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Essential for recycling GMP and indirectly, cGMP.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
95QVSKSGKTCILDIDMcurated19823750
125FLFIAPPSVEDLKKRcurated22369663
149ESINKRLSAAQAELAdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17330950; 17563356; 18407956; 16381945; 23193290;
157AAQAELAYAETGAHDPhosphoGRID 2.0;UniProt;curated19779198; 22817900
Sequence
(Fasta)		MSRPIVISGP SGTGKSTLLK KLFAEYPDSF GFSVSSTTRT PRAGEVNGKD YNFVSVDEFK 60
SMIKNNEFIE WAQFSGNYYG STVASVKQVS KSGKTCILDI DMQGVKSVKA IPELNARFLF 120
IAPPSVEDLK KRLEGRGTET EESINKRLSA AQAELAYAET GAHDKVIVND DLDKAYKELK 180
DFIFAEK 188
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR008145--GK/Ca_channel_bsu
IPR008144--Guanylate_kin-like_dom
IPR017665--Guanylate_kinase
IPR020590--Guanylate_kinase_CS
IPR027417--P-loop_NTPase
PROSITE

PS00856--GUANYLATE_KINASE_1
PS50052--GUANYLATE_KINASE_2
Pfam

PF00625--Guanylate_kin
Gene Ontology

GO:0005524--F:ATP binding
GO:0004385--F:guanylate kinase activity
GO:0046710--P:GDP metabolic process
GO:0046037--P:GMP metabolic process
GO:0006163--P:purine nucleotide metabolic process