| Tag |
Content |
| dbPAF ID |
dbPAF-0006048 |
| Uniprot Accession |
P15424; MS116_YEAST; D6VSH6;
|
| Genbank Protein ID |
NP_010480.1;
|
| Genbank Nucleotide ID |
NM_001180502.1;
|
| Protein Name |
ATP-dependent RNA helicase MSS116, mitochondrial |
| Protein Synonyms/Alias |
|
| Gene Name |
MSS116 |
| Gene Synonyms/Alias |
YDR194C;YD9346.05C; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.Functional Description
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MLTSILIKGR TPVLASRNLL AALSNCNHIT WAVSRRLYND GNRDQRNFGR NQRNNNSNRY 60
RNSRFNSRPR TRSREDDDEV HFDKTTFSKL IHVPKEDNSK EVTLDSLLEE GVLDKEIHKA 120
ITRMEFPGLT PVQQKTIKPI LSSEDHDVIA RAKTGTGKTF AFLIPIFQHL INTKFDSQYM 180
VKAVIVAPTR DLALQIEAEV KKIHDMNYGL KKYACVSLVG GTDFRAAMNK MNKLRPNIVI 240
ATPGRLIDVL EKYSNKFFRF VDYKVLDEAD RLLEIGFRDD LETISGILNE KNSKSADNIK 300
TLLFSATLDD KVQKLANNIM NKKECLFLDT VDKNEPEAHE RIDQSVVISE KFANSIFAAV 360
EHIKKQIKER DSNYKAIIFA PTVKFTSFLC SILKNEFKKD LPILEFHGKI TQNKRTSLVK 420
RFKKDESGIL VCTDVGARGM DFPNVHEVLQ IGVPSELANY IHRIGRTARS GKEGSSVLFI 480
CKDELPFVRE LEDAKNIVIA KQEKYEPSEE IKSEVLEAVT EEPEDISDIV ISLISSYRSC 540
IKEYRFSERR ILPEIASTYG VLLNDPQLKI PVSRRFLDKL GLSRSPIGKA MFEIRDYSSR 600
DGNNKSYDYD DDSEISFRGN KNYNNRSQNR DYDDEPFRRS NNNRRSFSRS NDKNNYSSRN 660
SNIY
665Fasta Sequence
>P15424|MSS116|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY
|
| Keyword |
KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0496--Mitochondrion
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0809--Transit peptide
KW-0810--Translation regulation
|
| Interpro |
IPR011545--DEAD/DEAH_box_helicase_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000629--RNA-helicase_DEAD-box_CS
IPR014014--RNA_helicase_DEAD_Q_motif
|
| PROSITE |
PS00039--DEAD_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51195--Q_MOTIF
|
| Pfam |
PF00270--DEAD
PF00271--Helicase_C
|
| Gene Ontology |
GO:0005759--C:mitochondrial matrix
GO:0005524--F:ATP binding
GO:0004004--F:ATP-dependent RNA helicase activity
GO:0003723--F:RNA binding
GO:0033592--F:RNA strand annealing activity
GO:0000372--P:Group I intron splicing
GO:0000373--P:Group II intron splicing
GO:0006397--P:mRNA processing
GO:0006417--P:regulation of translation
GO:0034337--P:RNA folding
GO:0010501--P:RNA secondary structure unwinding
GO:0006392--P:transcription elongation from mitochondrial promoter
|
