dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0006012
Uniprot Accession P15274; AMPD_YEAST; D6VZE0;
Genbank Protein ID NP_013677.1;
Genbank Nucleotide ID NM_001182392.1;
Protein Name AMP deaminase
Protein Synonyms/Alias Myoadenylate deaminase;
Gene Name AMD1
Gene Synonyms/Alias AMD;YML035C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 AMP deaminase plays a critical role in energy metabolism.
Phosphorylation Sites
 dbPAF PTMs: 19
PositionPeptidesSourceReferences ( PMIDs )
19LSLEPAPSHDEQDGSdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 21081558; 19060867;
26SHDEQDGSGLVIDIDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040406; 22369663;
50GVVVDDETPPLEQQDPhosphoGRID 2.0;curated19779198; 26040406; 23825934; 25315811
58PPLEQQDSHESLAADdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 19779198;
61EQQDSHESLAADSRNdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 19779198;
66HESLAADSRNANFSYPhosphoPep 2.0;curated19060867; 26040406; 25315811
103SAILEQPSHSTNCSScurated19823750
105ILEQPSHSTNCSSSNPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 20377248
109PSHSTNCSSSNIAAMPhosphoGRID 2.019779198
110SHSTNCSSSNIAAMNPhosphoPep 2.019060867
122AMNKGHDSADHASQNcurated19823750
127HDSADHASQNSGGKPcurated19823750
130ADHASQNSGGKPRTLcurated25315811
136NSGGKPRTLSASAQHdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 16381945; 23193290; 21177495; 20702584; 19823750;
138GGKPRTLSASAQHILdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17287358; 17330950; 17563356; 18407956; 16381945;
140KPRTLSASAQHILPEdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 19779198; 19060867;
299QIPTLRDYYLDLEKMcurated25882841
308LDLEKMISISSDGPAcurated25882841
320GPAKSFAYRRLQYLEcurated25882841
Sequence
(Fasta)		MDNQATQRLN DLSLEPAPSH DEQDGSGLVI DIDQRKIGDE QAGVVVDDET PPLEQQDSHE 60
SLAADSRNAN FSYHENQQLL ENGTKQLALD EHDSHSAILE QPSHSTNCSS SNIAAMNKGH 120
DSADHASQNS GGKPRTLSAS AQHILPETLK SFAGAPVVNK QVRTSASYKM GMLADDASQQ 180
FLDDPSSELI DLYSKVAECR NLRAKYQTIS VQNDDQNPKN KPGWVVYPPP PKPSYNSDTK 240
TVVPVTNKPD AEVFDFTKCE IPGEDPDWEF TLNDDDSYVV HRSGKTDELI AQIPTLRDYY 300
LDLEKMISIS SDGPAKSFAY RRLQYLEARW NLYYLLNEYQ ETSVSKRNPH RDFYNVRKVD 360
THVHHSACMN QKHLLRFIKH KLRHSKDEKV IFRDGKLLTL DEVFRSLHLT GYDLSIDTLD 420
MHAHKDTFHR FDKFNLKYNP IGESRLREIF LKTNNYIKGT YLADITKQVI FDLENSKYQN 480
CEYRISVYGR SLDEWDKLAS WVIDNKVISH NVRWLVQIPR LYDIYKKTGI VQSFQDICKN 540
LFQPLFEVTK NPQSHPKLHV FLQRVIGFDS VDDESKVDRR FHRKYPKPSL WEAPQNPPYS 600
YYLYYLYSNV ASLNQWRAKR GFNTLVLRPH CGEAGDPEHL VSAYLLAHGI SHGILLRKVP 660
FVQYLYYLDQ VGIAMSPLSN NALFLTYDKN PFPRYFKRGL NVSLSTDDPL QFSYTREPLI 720
EEYSVAAQIY KLSNVDMCEL ARNSVLQSGW EAQIKKHWIG KDFDKSGVEG NDVVRTNVPD 780
IRINYRYDTL STELELVNHF ANFKRTIEEK 811
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0546--Nucleotide metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR006650--A/AMP_deam_AS
IPR001365--A/AMP_deaminase_dom
IPR006329--AMPD
IPR032466--Metal_Hydrolase
PROSITE

PS00485--A_DEAMINASE
Pfam

PF00962--A_deaminase
Gene Ontology

GO:0003876--F:AMP deaminase activity
GO:0046872--F:metal ion binding
GO:0006178--P:guanine salvage
GO:0032264--P:IMP salvage
GO:0006163--P:purine nucleotide metabolic process