dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005999
Uniprot Accession P15180; SYKC_YEAST; D6VS25;
Genbank Protein ID NP_010322.1;
Genbank Nucleotide ID NM_001180345.1;
Protein Name Lysine--tRNA ligase, cytoplasmic
Protein Synonyms/Alias Lysyl-tRNA synthetase;LysRS;
Gene Name KRS1
Gene Synonyms/Alias GCD5;YDR037W;YD9673.09;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
30TGEMVSKSELKKRIKdbPTM 3.0;SysPTM 2.0;UniProt18407956; 16381945; 23193290; 19366988
62KPASKKKTDLFADLDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17330950; 17563356; 18407956; 16381945; 23193290;
71LFADLDPSQYFETRScurated22369663; 23825934
73ADLDPSQYFETRSRQcurated23825934
102HKFHVSISNPEFLAKcurated22369663
136RIHAKRESGSKLKFYPhosphoGRID 2.021126336
138HAKRESGSKLKFYVLcurated22817900; 19823750
371MVKEITGSYIIKYHPcurated22369663; 24961812
Sequence
(Fasta)		MSQQDNVKAA AEGVANLHLD EATGEMVSKS ELKKRIKQRQ VEAKKAAKKA AAQPKPASKK 60
KTDLFADLDP SQYFETRSRQ IQELRKTHEP NPYPHKFHVS ISNPEFLAKY AHLKKGETLP 120
EEKVSIAGRI HAKRESGSKL KFYVLHGDGV EVQLMSQLQD YCDPDSYEKD HDLLKRGDIV 180
GVEGYVGRTQ PKKGGEGEVS VFVSRVQLLT PCLHMLPADH FGFKDQETRY RKRYLDLIMN 240
KDARNRFITR SEIIRYIRRF LDQRKFIEVE TPMMNVIAGG ATAKPFITHH NDLDMDMYMR 300
IAPELFLKQL VVGGLDRVYE IGRQFRNEGI DMTHNPEFTT CEFYQAYADV YDLMDMTELM 360
FSEMVKEITG SYIIKYHPDP ADPAKELELN FSRPWKRINM IEELEKVFNV KFPSGDQLHT 420
AETGEFLKKI LVDNKLECPP PLTNARMLDK LVGELEDTCI NPTFIFGHPQ MMSPLAKYSR 480
DQPGLCERFE VFVATKEICN AYTELNDPFD QRARFEEQAR QKDQGDDEAQ LVDETFCNAL 540
EYGLPPTGGW GCGIDRLAMF LTDSNTIREV LLFPTLKPDV LREEVKKEEE N 592
Keyword

KW-0007--Acetylation
KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR004364--aa-tRNA-synt_II
IPR018150--aa-tRNA-synt_II-like
IPR006195--aa-tRNA-synth_II
IPR002313--Lys-tRNA-ligase_II
IPR018149--Lys-tRNA-synth_II_C
IPR012340--NA-bd_OB-fold
IPR004365--NA-bd_OB_tRNA
PROSITE

PS50862--AA_TRNA_LIGASE_II
Pfam

PF00152--tRNA-synt_2
PF01336--tRNA_anti-codon
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004824--F:lysine-tRNA ligase activity
GO:0003676--F:nucleic acid binding
GO:0006430--P:lysyl-tRNA aminoacylation