dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005950
Uniprot Accession P14843; AROF_YEAST; D6VS23;
Genbank Protein ID NP_010320.3;
Genbank Nucleotide ID NM_001180343.3;
Protein Name Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited
Protein Synonyms/Alias 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase;DAHP synthase;Phospho-2-keto-3-deoxyheptonate aldolase;
Gene Name ARO3
Gene Synonyms/Alias YDR035W;YD9673.07;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
26IKGYDPLTPPDLLQHdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 19366988; 22369663;
51NIIKARDSVCDILNGcurated25315811
Sequence
(Fasta)		MFIKNDHAGD RKRLEDWRIK GYDPLTPPDL LQHEFPISAK GEENIIKARD SVCDILNGKD 60
DRLVIVIGPC SLHDPKAAYD YADRLAKISE KLSKDLLIIM RAYLEKPRTT VGWKGLINDP 120
DMNNSFQINK GLRISREMFI KLVEKLPIAG EMLDTISPQF LSDCFSLGAI GARTTESQLH 180
RELASGLSFP IGFKNGTDGG LQVAIDAMRA AAHEHYFLSV TKPGVTAIVG TEGNKDTFLI 240
LRGGKNGTNF DKESVQNTKK QLEKAGLTDD SQKRIMIDCS HGNSNKDFKN QPKVAKCIYD 300
QLTEGENSLC GVMIESNINE GRQDIPKEGG REGLKYGCSV TDACIGWEST EQVLELLAEG 360
VRNRRKALKK 371
Keyword

KW-0028--Amino-acid biosynthesis
KW-0057--Aromatic amino acid biosynthesis
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0346--Stress response
KW-0808--Transferase
Interpro

IPR013785--Aldolase_TIM
IPR006218--DAHP1/KDSA
IPR006219--DHAP_synth_1
PROSITE
Pfam

PF00793--DAHP_synth_1
Gene Ontology

GO:0003849--F:3-deoxy-7-phosphoheptulonate synthase activity
GO:0009073--P:aromatic amino acid family biosynthetic process
GO:0009423--P:chorismate biosynthetic process