| Tag |
Content |
| dbPAF ID |
dbPAF-0005945 |
| Uniprot Accession |
P14785; CCNA_DROME; Q8IGR7; Q9VTP6; Q9VTP7;
|
| Genbank Protein ID |
NP_524030.2;
|
| Genbank Nucleotide ID |
NM_079306.4;
|
| Protein Name |
G2/mitotic-specific cyclin-A |
| Protein Synonyms/Alias |
|
| Gene Name |
CycA |
| Gene Synonyms/Alias |
CG5940; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the Cdk1 and Cdk2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.Functional Description
Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the Cdk1 and Cdk2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MASFQIHQDM SNKENPGIKI PAGVKNTKQP LAVIGGKAEK NALAPRANFA VLNGNNNVPR 60
PAGKVQVFRD VRNLNVDENV EYGAKKSNVV PVVEQFKTFS VYEDNNDTQV APSGKSLASL 120
VDKENHDVKF GAGQKELVDY DLDSTPMSVT DVQSPMSVDR SILGVIQSSD ISVGTETGVS 180
PTGRVKELPP RNDRQRFLEV VQYQMDILEY FRESEKKHRP KPLYMRRQKD ISHNMRSILI 240
DWLVEVSEEY KLDTETLYLS VFYLDRFLSQ MAVVRSKLQL VGTAAMYIAA KYEEIYPPEV 300
GEFVFLTDDS YTKAQVLRME QVILKILSFD LCTPTAYVFI NTYAVLCDMP EKLKYMTLYI 360
SELSLMEGET YLQYLPSLMS SASVALARHI LGMEMWTPRL EEITTYKLED LKTVVLHLCH 420
THKTAKELNT QAMREKYNRD TYKKVAMMES VEMSKDDFDQ LCEAYNCKQK EDEHQQPDIN 480
TKSNVNLFYK F
492Fasta Sequence
>P14785|CycA|Drosophila melanogaster(Fruit fly)
MASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVAMMESVEMSKDDFDQLCEAYNCKQKEDEHQQPDINTKSNVNLFYKF
|
| Keyword |
KW-0025--Alternative splicing
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0195--Cyclin
KW-0498--Mitosis
KW-1185--Reference proteome
|
| Interpro |
IPR013763--Cyclin-like
IPR004367--Cyclin_C-dom
IPR006671--Cyclin_N
|
| PROSITE |
PS00292--CYCLINS
|
| Pfam |
PF02984--Cyclin_C
PF00134--Cyclin_N
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0045169--C:fusome
GO:0005634--C:nucleus
GO:0045170--C:spectrosome
GO:0016538--F:cyclin-dependent protein serine/threonine kinase regulator activity
GO:0055059--P:asymmetric neuroblast division
GO:0046331--P:lateral inhibition
GO:0007067--P:mitotic nuclear division
GO:0000070--P:mitotic sister chromatid segregation
GO:0045841--P:negative regulation of mitotic metaphase/anaphase transition
GO:0022008--P:neurogenesis
GO:0007422--P:peripheral nervous system development
GO:0035561--P:regulation of chromatin binding
GO:0007096--P:regulation of exit from mitosis
GO:0009794--P:regulation of mitotic cell cycle, embryonic
GO:0007088--P:regulation of mitotic nuclear division
GO:0045859--P:regulation of protein kinase activity
GO:0035186--P:syncytial blastoderm mitotic cell cycle
|
