dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005941
Uniprot Accession P14772; BPT1_YEAST; D6VXY7;
Genbank Protein ID NP_013086.1;
Genbank Nucleotide ID NM_001181835.1;
Protein Name Bile pigment transporter 1
Protein Synonyms/Alias
Gene Name BPT1
Gene Synonyms/Alias YLL015W;L1313;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Cooperates for the ATP-dependent vacuolar transport of bilirubin and glutathione conjugates.
Phosphorylation Sites
dbPAF PTMs: 21 (View all)
PositionPeptidesSourceReferences ( PMIDs )
632KSKEVLTSSQSGDNLcurated24961812
633SKEVLTSSQSGDNLRcurated24961812; 25315811
635EVLTSSQSGDNLRTDcurated25315811
641QSGDNLRTDEESIIGdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 25315811
645NLRTDEESIIGSSQIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17330950; 18407956; 16381945; 23193290; 19779198;
885PIDNGNESDVQTEHRdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;UniProt;curated17563356; 16381945; 23193290; 19779198; 21081558; 26040289;
889GNESDVQTEHRSESEPhosphoGRID 2.0;PHOSIDA;UniProt;curated19779198; 21081558; 22817900; 19795423; 25315811; 20377248
893DVQTEHRSESEVDEPPhosphoGRID 2.0;UniProt;curated21126336; 19779198; 26040289; 22817900; 25315811; 20377248
895QTEHRSESEVDEPLQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20702584; 19779198; 19366988;
906EPLQLKVTESETEDEdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 22817900;
908LQLKVTESETEDEVVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 17330950; 19366988; 22817900;
910LKVTESETEDEVVTEcurated22817900; 20377248
916ETEDEVVTESELELIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 17330950; 19060867; 19366988;
918EDEVVTESELELIKAcurated22817900
927LELIKANSRRASLATdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19366988; 22817900; 19823750;
931KANSRRASLATLRPRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19366988; 26040289; 22817900;
934SRRASLATLRPRPFVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19366988; 26040289; 22817900;
947FVGAQLDSVKKTAQKcurated19823750
1045RSIMMLLYCSIRGSKcurated26040406
1047IMMLLYCSIRGSKKLcurated26040406
Sequence
(Fasta)
MSSLEVVDGC PYGYRPYPDS GTNALNPCFI SVISAWQAVF FLLIGSYQLW KLYKNNKVPP 60
RFKNFPTLPS KINSRHLTHL TNVCFQSTLI ICELALVSQS SDRVYPFILK KALYLNLLFN 120
LGISLPTQYL AYFKSTFSMG NQLFYYMFQI LLQLFLILQR YYHGSSNERL TVISGQTAMI 180
LEVLLLFNSV AIFIYDLCIF EPINELSEYY KKNGWYPPVH VLSYITFIWM NKLIVETYRN 240
KKIKDPNQLP LPPVDLNIKS ISKEFKANWE LEKWLNRNSL WRAIWKSFGR TISVAMLYET 300
TSDLLSVVQP QFLRIFIDGL NPETSSKYPP LNGVFIALTL FVISVVSVFL TNQFYIGIFE 360
AGLGIRGSLA SLVYQKSLRL TLAERNEKST GDILNLMSVD VLRIQRFFEN AQTIIGAPIQ 420
IIVVLTSLYW LLGKAVIGGL VTMAIMMPIN AFLSRKVKKL SKTQMKYKDM RIKTITELLN 480
AIKSIKLYAW EEPMMARLNH VRNDMELKNF RKIGIVSNLI YFAWNCVPLM VTCSTFGLFS 540
LFSDSPLSPA IVFPSLSLFN ILNSAIYSVP SMINTIIETS VSMERLKSFL LSDEIDDSFI 600
ERIDPSADER ALPAIEMNNI TFLWKSKEVL TSSQSGDNLR TDEESIIGSS QIALKNIDHF 660
EAKRGDLVCV VGRVGAGKST FLKAILGQLP CMSGSRDSIP PKLIIRSSSV AYCSQESWIM 720
NASVRENILF GHKFDQDYYD LTIKACQLLP DLKILPDGDE TLVGEKGISL SGGQKARLSL 780
ARAVYSRADI YLLDDILSAV DAEVSKNIIE YVLIGKTALL KNKTIILTTN TVSILKHSQM 840
IYALENGEIV EQGNYEDVMN RKNNTSKLKK LLEEFDSPID NGNESDVQTE HRSESEVDEP 900
LQLKVTESET EDEVVTESEL ELIKANSRRA SLATLRPRPF VGAQLDSVKK TAQKAEKTEV 960
GRVKTKIYLA YIKACGVLGV VLFFLFMILT RVFDLAENFW LKYWSESNEK NGSNERVWMF 1020
VGVYSLIGVA SAAFNNLRSI MMLLYCSIRG SKKLHESMAK SVIRSPMTFF ETTPVGRIIN 1080
RFSSDMDAVD SNLQYIFSFF FKSILTYLVT VILVGYNMPW FLVFNMFLVV IYIYYQTFYI 1140
VLSRELKRLI SISYSPIMSL MSESLNGYSI IDAYDHFERF IYLNYEKIQY NVDFVFNFRS 1200
TNRWLSVRLQ TIGATIVLAT AILALATMNT KRQLSSGMVG LLMSYSLEVT GSLTWIVRTT 1260
VTIETNIVSV ERIVEYCELP PEAQSINPEK RPDENWPSKG GIEFKNYSTK YRENLDPVLN 1320
NINVKIEPCE KVGIVGRTGA GKSTLSLALF RILEPTEGKI IIDGIDISDI GLFDLRSHLA 1380
IIPQDAQAFE GTVKTNLDPF NRYSEDELKR AVEQAHLKPH LEKMLHSKPR GDDSNEEDGN 1440
VNDILDVKIN ENGSNLSVGQ RQLLCLARAL LNRSKILVLD EATASVDMET DKIIQDTIRR 1500
EFKDRTILTI AHRIDTVLDS DKIIVLDQGS VREFDSPSKL LSDKTSIFYS LCEKGGYLK 1560
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0926--Vacuole

Interpro

IPR003593--AAA+_ATPase
IPR011527--ABC1_TM_dom
IPR003439--ABC_transporter-like
IPR017871--ABC_transporter_CS
IPR027417--P-loop_NTPase

PROSITE

PS50929--ABC_TM1F
PS00211--ABC_TRANSPORTER_1
PS50893--ABC_TRANSPORTER_2

Pfam

PF00664--ABC_membrane
PF00005--ABC_tran

Gene Ontology

GO:0000329--C:fungal-type vacuole membrane
GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0042626--F:ATPase activity, coupled to transmembrane movement of substances
GO:0015127--F:bilirubin transmembrane transporter activity
GO:0015086--F:cadmium ion transmembrane transporter activity
GO:0015723--P:bilirubin transport
GO:0070574--P:cadmium ion transmembrane transport
GO:0015691--P:cadmium ion transport
GO:0042144--P:vacuole fusion, non-autophagic