dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005939
Uniprot Accession P14747; PP2B2_YEAST; D6VZB7;
Genbank Protein ID NP_013655.1;
Genbank Nucleotide ID NM_001182415.1;
Protein Name Serine/threonine-protein phosphatase 2B catalytic subunit A2
Protein Synonyms/Alias Calcineurin A2;Calmodulin-binding protein 2;
Gene Name CMP2
Gene Synonyms/Alias CNA2;YML057W;YM9958.05;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
28NKTERPQSSTTPIDScurated26040289; 22369663; 25315811
29KTERPQSSTTPIDSKcurated26040289; 20377248
30TERPQSSTTPIDSKAdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 22817900;
31ERPQSSTTPIDSKASdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 20489023;
38TPIDSKASTVAAANSPhosphoGRID 2.020489023
39PIDSKASTVAAANSTPhosphoGRID 2.020489023
302EVLDKDLTEEDIVNScurated22817900; 25315811
478KLPQAGKSEATPQPAPhosphoGRID 2.021126336
481QAGKSEATPQPATSAcurated26040406; 22369663; 25315811
489PQPATSASPKHASILdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20489023; 21126336; 19779198;
Sequence
(Fasta)		MSSDAIRNTE QINAAIKIIE NKTERPQSST TPIDSKASTV AAANSTATET SRDLTQYTLD 60
DGRVVSTNRR IMNKVPAITS HVPTDEELFQ PNGIPRHEFL RDHFKREGKL SAAQAARIVT 120
LATELFSKEP NLISVPAPIT VCGDIHGQYF DLLKLFEVGG DPATTSYLFL GDYVDRGSFS 180
FECLIYLYSL KLNFNDHFWL LRGNHECKHL TSYFTFKNEM LHKYNLDIYE KCCESFNNLP 240
LAALMNGQYL CVHGGISPEL NSLQDINNLN RFREIPSHGL MCDLLWADPI EEYDEVLDKD 300
LTEEDIVNSK TMVPHHGKMA PSRDMFVPNS VRGCSYAFTY RAACHFLQET GLLSIIRAHE 360
AQDAGYRMYK NTKTLGFPSL LTLFSAPNYL DTYNNKAAIL KYENNVMNIR QFNMTPHPYW 420
LPDFMDVFTW SLPFVGEKVT EMLVAILNIC TEDELENDTP VIEELVGTDK KLPQAGKSEA 480
TPQPATSASP KHASILDDEH RRKALRNKIL AVAKVSRMYS VLREETNKVQ FLKDHNSGVL 540
PRGALSNGVK GLDEALSTFE RARKHDLINE KLPPSLDELK NENKKYYEKV WQKVHEHDAK 600
NDSK 605
Keyword

KW-0112--Calmodulin-binding
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0408--Iron
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0904--Protein phosphatase
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR004843--Calcineurin-like_PHP_apaH
IPR029052--Metallo-depent_PP-like
IPR006186--Ser/Thr-sp_prot-phosphatase
PROSITE

PS00125--SER_THR_PHOSPHATASE
Pfam

PF00149--Metallophos
Gene Ontology

GO:0005955--C:calcineurin complex
GO:0046872--F:metal ion binding
GO:0004721--F:phosphoprotein phosphatase activity
GO:0000754--P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
GO:0006873--P:cellular ion homeostasis
GO:0006470--P:protein dephosphorylation