dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005936
Uniprot Accession P14737; RAD9_YEAST; D6VSK0; Q04920;
Genbank Protein ID NP_010503.1;
Genbank Nucleotide ID NM_001180525.1;
Protein Name DNA repair protein RAD9
Protein Synonyms/Alias
Gene Name RAD9
Gene Synonyms/Alias YDR217C;YD9934.02C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase.
Phosphorylation Sites
 dbPAF PTMs: 78 (View all)
PositionPeptidesSourceReferences ( PMIDs )
10GQLVQWKSSPDRVTQdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 22369663; 22817900; 19823750;
11QLVQWKSSPDRVTQSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 17563356; 16381945; 23193290; 20700441; 15972895;
26AIKEALHSPLADGDMdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 15972895; 19366988;
49PLENKVNSTNIIEGSPhosphoGRID 2.0;curated21126336; 25704821
50LENKVNSTNIIEGSPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
56STNIIEGSPKANPNPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20702584; 19823750; 19779198;
70PVKFMNTSEIFQKSLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
76TSEIFQKSLGLLDESdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
83SLGLLDESPRHDDELdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289
125NFFKSNRTPGKENLLPhosphoPep 2.019060867
135KENLLTKYQSSDLEDcurated19823750; 20377248
137NLLTKYQSSDLEDTPdbPTM 3.0;PhosphoGRID 2.0;curated18407956; 16381945; 23193290; 19823750; 19795423; 22817900;
138LLTKYQSSDLEDTPLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19823750; 19795423; 19366988;
143QSSDLEDTPLMLRKKcurated24961812; 25315811
152LMLRKKMTFQTPTDPcurated22817900; 25521595; 19547744
155RKKMTFQTPTDPLEQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900; 19547744
188NDGEENASLEVTEADdbPTM 3.018407956; 16381945; 23193290
192ENASLEVTEADATFVPhosphoGRID 2.011124038
205FVQMAERSADNYDCAdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 15972895; 19366988; 25315811
218CALEGIVTPKRYKDEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 26040289; 25315811
Sequence
(Fasta)		MSGQLVQWKS SPDRVTQSAI KEALHSPLAD GDMNEMNVPV DPLENKVNST NIIEGSPKAN 60
PNPVKFMNTS EIFQKSLGLL DESPRHDDEL NIEVGDNDRP NANILHNERT PDLDRIANFF 120
KSNRTPGKEN LLTKYQSSDL EDTPLMLRKK MTFQTPTDPL EQKTFKKLKS DTGFCYYGEQ 180
NDGEENASLE VTEADATFVQ MAERSADNYD CALEGIVTPK RYKDELSKSG GMQDERVQKT 240
QIMISAESPN SISSYDKNKI TGNGRTTRNV NKVFNNNEDN IGAIEEKNPV KKKSENYSSD 300
DLRERNNQII QSNESEEINE LEKNLNVSGR ENDVNNLDID INSAVSGTPS RNNAEEEMYS 360
SESVNNREPS KKWIFRYSKD KTENNSNRST QIVNNPRTQE MPLDSISIDT QPLSKSFNTE 420
TNNELETQII VSSLSQGISA QKGPVFHSTG QTEEIKTQII NSPEQNALNA TFETPVTLSR 480
INFEPILEVP ETSSPSKNTM SKPSNSSPIP KEKDTFNIHE REVETNNVFS NDIQNSSNAA 540
TRDDIIIAGS SDFNEQKEIT DRIYLQLSGK QISDSGSDET ERMSPNELDT KKESTIMSEV 600
ELTQELPEVE EQQDLQTSPK KLVVEEETLM EIKKSKGNSL QLHDDNKECN SDKQDGTESL 660
DVALIEHESK GQSSELQKNL MQLFPSESQE IIQNRRTIKR RQKDTIEIGE EEENRSTKTS 720
PTKHLKRNSD LDAASIKREP SCSITIQTGE TGSGKDSKEQ SYVFPEGIRT ADNSFLSKDD 780
IIFGNAVWCQ YTWNYKFYPG ILLEVDTNQD GCWIYFETGR SLTKDEDIYY LDIRIGDAVT 840
FDGNEYVVVG LECRSHDLNI IRCIRGYDTV HLKKKNASGL LGKRTLIKAL SSISLDLSEW 900
AKRAKIILED NEKNKGDAYR YLRHPIRGRK SMTNVLSPKK HTDDEKDINT HTEVYNNEIE 960
SSSEKKEIVK KDSRDALAEH AGAPSLLFSS GEIRTGNVFD KCIFVLTSLF ENREELRQTI 1020
ESQGGTVIES GFSTLFNFTH PLAKSLVNKG NTDNIRELAL KLAWKPHSLF ADCRFACLIT 1080
KRHLRSLKYL ETLALGWPTL HWKFISACIE KKRIVPHLIY QYLLPSGESF RLSLDSPSKG 1140
GIIKSNNIFS FYTQFLRGSN LRDQICGVKK MLNDYIVIVW GRSELDSFVK FAFACLSAGR 1200
MLTIDLPNID VDDTEPLLNA LDSLVPRIGS ELSNRKLKFL IYANENNGKS QMKLLERLRS 1260
QISLKFKKFN YIFHTESKEW LIQTIINEDT GFHDDITDND IYNTISEVR
Keyword

KW-0002--3D-structure
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0236--DNA replication inhibitor
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR001357--BRCT_dom
IPR013914--Rad9_Rad53-bd_dom_fun
PROSITE

PS50172--BRCT
Pfam

PF00533--BRCT
PF08605--Rad9_Rad53_bind
Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0003690--F:double-stranded DNA binding
GO:0008047--F:enzyme activator activity
GO:0042393--F:histone binding
GO:0000077--P:DNA damage checkpoint
GO:0006281--P:DNA repair
GO:0044783--P:G1 DNA damage checkpoint
GO:0031573--P:intra-S DNA damage checkpoint
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:0008156--P:negative regulation of DNA replication
GO:0006289--P:nucleotide-excision repair
GO:0043085--P:positive regulation of catalytic activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0051726--P:regulation of cell cycle