dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005935
Uniprot Accession P14736; RAD4_YEAST; D3DM70;
Genbank Protein ID NP_011089.4;
Genbank Nucleotide ID NM_001179052.4;
Protein Name DNA repair protein RAD4
Protein Synonyms/Alias
Gene Name RAD4
Gene Synonyms/Alias YER162C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
236TWKEIEMSANNKRKFcurated26040289
376KYGCRDVTRRYAQWMcurated22817900
730SVDKAEESATDDDVGcurated25315811
740DDDVGEDYSDFMKELcurated25315811
753ELEMSEESD------curated25315811
Sequence
(Fasta)		MNEDLPKEYF ELIRKALNEK EAEKAPLSRR RRVRRKNQPL PDAKKKFKTG LNELPRESVV 60
TVNLDSSDDG VVTVPTDDSV EEIQSSEEDY DSEEFEDVTD GNEVAGVEDI SVEIKPSSKR 120
NSDARRTSRN VCSNEERKRR KYFHMLYLVC LMVHGFIRNE WINSKRLSRK LSNLVPEKVF 180
ELLHPQKDEE LPLRSTRKLL DGLKKCMELW QKHWKITKKY DNVGLYMRTW KEIEMSANNK 240
RKFKTLKRSD FLRAVSKGHG DPDISVQGFV AMLRACNVNA RLIMSCQPPD FTNMKIDTSL 300
NGNNAYKDMV KYPIFWCEVW DKFSKKWITV DPVNLKTIEQ VRLHSKLAPK GVACCERNML 360
RYVIAYDRKY GCRDVTRRYA QWMNSKVRKR RITKDDFGEK WFRKVITALH HRKRTKIDDY 420
EDQYFFQRDE SEGIPDSVQD LKNHPYYVLE QDIKQTQIVK PGCKECGYLK VHGKVGKVLK 480
VYAKRDIADL KSARQWYMNG RILKTGSRCK KVIKRTVGRP KGEAEEEDER LYSFEDTELY 540
IPPLASASGE ITKNTFGNIE VFAPTMIPGN CCLVENPVAI KAARFLGVEF APAVTSFKFE 600
RGSTVKPVLS GIVVAKWLRE AIETAIDGIE FIQEDDNRKE HLLGALESWN TLLLKLRIRS 660
KLNSTYGKIA EEEPNVTKEQ NIADNHDNTE TFMGGGFLPG IANHEARPYS EPSEPEDSLD 720
YVSVDKAEES ATDDDVGEDY SDFMKELEMS EESD 755
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR004583--DNA_repair_Rad4
IPR018325--Rad4/PNGase_transGLS-fold
IPR018326--Rad4_beta-hairpin_dom1
IPR018327--Rad4_beta-hairpin_dom2
IPR018328--Rad4_beta-hairpin_dom3
PROSITE
Pfam

PF10403--BHD_1
PF10404--BHD_2
PF10405--BHD_3
PF03835--Rad4
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0000111--C:nucleotide-excision repair factor 2 complex
GO:0005634--C:nucleus
GO:0071942--C:XPC complex
GO:0003684--F:damaged DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0006298--P:mismatch repair
GO:0006289--P:nucleotide-excision repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process