dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005927
Uniprot Accession P14682; UBC3_YEAST; D6VS40;
Genbank Protein ID NP_010339.1;
Genbank Nucleotide ID NM_001180362.1;
Protein Name Ubiquitin-conjugating enzyme E2-34 kDa
Protein Synonyms/Alias Cell division control protein 34;E2 ubiquitin-conjugating enzyme 3;E3 ubiquitin ligase complex SCF subunit CDC34;Ubiquitin carrier protein;Ubiquitin-protein ligase;
Gene Name CDC34
Gene Synonyms/Alias DNA6;UBC3;YDR054C;D4211;YD9609.08C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Catalyzes the covalent attachment of ubiquitin to other proteins. Capable, in vitro, to ubiquitinate histone H2A.
Phosphorylation Sites
 dbPAF PTMs: 12
PositionPeptidesSourceReferences ( PMIDs )
10SRKSTASSLLLRQYRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
182FIMPTSESAYISQSKdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
184MPTSESAYISQSKLDcurated25315811
186TSESAYISQSKLDEPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22817900; 24961812;
188ESAYISQSKLDEPESdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 24961812
195SKLDEPESNKDMADNcurated25521595; 25315811
207ADNFWYDSDLDDDENPhosphoGRID 2.017461777; 16952051
216LDDDENGSVILQDDDPhosphoGRID 2.017461777
263DDDDDDDSIDNDSVMPHOSIDA;curated21081558; 26040289; 25704821; 22369663; 22817900; 25315811
268DDSIDNDSVMDRKQPcurated26040289; 25704821
282PHKAEDESEDVEDVEPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;UniProt;curated21177495; 21126336; 19779198; 16952051; 21081558; 19060867;
292VEDVERVSKKI----dbPTM 3.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 24961812; 25315811
Sequence
(Fasta)		MSSRKSTASS LLLRQYRELT DPKKAIPSFH IELEDDSNIF TWNIGVMVLN EDSIYHGGFF 60
KAQMRFPEDF PFSPPQFRFT PAIYHPNVYR DGRLCISILH QSGDPMTDEP DAETWSPVQT 120
VESVLISIVS LLEDPNINSP ANVDAAVDYR KNPEQYKQRV KMEVERSKQD IPKGFIMPTS 180
ESAYISQSKL DEPESNKDMA DNFWYDSDLD DDENGSVILQ DDDYDDGNNH IPFEDDDVYN 240
YNDNDDDDER IEFEDDDDDD DDSIDNDSVM DRKQPHKAED ESEDVEDVER VSKKI 296
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0235--DNA replication
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD
PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2
Pfam

PF00179--UQ_con
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042803--F:protein homodimerization activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0051301--P:cell division
GO:0006260--P:DNA replication
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process