dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005868
Uniprot Accession P14180; CHS2_YEAST; D6VQ38;
Genbank Protein ID NP_009594.1;
Genbank Nucleotide ID NM_001178386.1;
Protein Name Chitin synthase 2
Protein Synonyms/Alias Chitin-UDP acetyl-glucosaminyl transferase 2;
Gene Name CHS2
Gene Synonyms/Alias YBR038W;YBR0407;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Essential for septum formation and cell division. CHS2 is required for maintaining normal cell morphology.
Phosphorylation Sites
 dbPAF PTMs: 26 (View all)
PositionPeptidesSourceReferences ( PMIDs )
11NPFMVEPSNGSPNRRdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
14MVEPSNGSPNRRGASdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19060867; 19366988; 22817900;
40NSRWANPSEESLEDSPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19684113; 19779198; 19060867; 22817900
43WANPSEESLEDSYDQPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19779198; 19060867; 22817900
51LEDSYDQSNVFQGLPPhosphoGRID 2.019779198
60VFQGLPASPSRAALRPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19779198; 19060867; 22817900
69SRAALRYSPDRRHRTdbPTM 3.0;PhosphoGRID 2.0;curated17563356; 16381945; 23193290; 22817900
76SPDRRHRTQFYRDSAPhosphoPep 2.019060867
79RRHRTQFYRDSAHNSPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 22817900
82RTQFYRDSAHNSPVAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated11875433; 17563356; 18407956; 16381945; 23193290; 21177495;
86YRDSAHNSPVAPNRYdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated11875433; 17563356; 18407956; 16381945; 23193290; 21177495;
100YAANLQESPKRAGEAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated17563356; 16381945; 23193290; 21177495; 20702584; 19779198;
130ADLPVDPYHLSPQQQPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19060867; 22369663; 22817900
133PVDPYHLSPQQQPSNdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19779198; 19060867;
145PSNNLFGSGRLYSQSPhosphoGRID 2.0;curated19779198; 22817900
166TTSTTAPSLAEADDEcurated24961812
177ADDEKEKYLTSTTSYcurated26040289
179DEKEKYLTSTTSYDDcurated26040289
181KEKYLTSTTSYDDQScurated26040289
184YLTSTTSYDDQSTIFcurated26040289
Sequence
(Fasta)		MTRNPFMVEP SNGSPNRRGA SNLSKFYANA NSNSRWANPS EESLEDSYDQ SNVFQGLPAS 60
PSRAALRYSP DRRHRTQFYR DSAHNSPVAP NRYAANLQES PKRAGEAVIH LSEGSNLYPR 120
DNADLPVDPY HLSPQQQPSN NLFGSGRLYS QSSKYTMSTT STTAPSLAEA DDEKEKYLTS 180
TTSYDDQSTI FSADTFNETK FELNHPTRQQ YVRRANSESK RRMVSDLPPP SKKKALLKLD 240
NPIPKGLLDT LPRRNSPEFT EMRYTACTVE PDDFLREGYT LRFAEMNREC QIAICITMYN 300
EDKYSLARTI HSIMKNVAHL CKREKSHVWG PNGWKKVSVI LISDGRAKVN QGSLDYLAAL 360
GVYQEDMAKA SVNGDPVKAH IFELTTQVSI NADLDYVSKD IVPVQLVFCL KEENKKKINS 420
HRWLFNAFCP VLQPTVVTLV DVGTRLNNTA IYRLWKVFDM DSNVAGAAGQ IKTMKGKWGL 480
KLFNPLVASQ NFEYKISNIL DKPLESVFGY ISVLPGALSA YRYRALKNHE DGTGPLRSYF 540
LGETQEGRDH DVFTANMYLA EDRILCWELV AKRDAKWVLK YVKEATGETD VPEDVSEFIS 600
QRRRWLNGAM FAAIYAQLHF YQIWKTKHSV VRKFFLHVEF LYQFIQMLFS WFSIANFVLT 660
FYYLAGSMNL VIKHGEALFI FFKYLIFCDL ASLFIISMGN RPQGAKHLFI TSMVILSICA 720
TYSLICGFVF AFKSLASGTE SHKIFVDIVI SLLSTYGLYF FSSLMYLDPW HMFTSSIQYF 780
LTLPAFTCTL QIFAFCNTHD VSWGTKGSTQ ESKQLSKAIV VQGPDGKQIV ETDWPQEVDK 840
KFLEIKSRLK EPEFEESSGN EKQSKNDYYR DIRTRIVMIW MLSNLILIMS IIQVFTPQDT 900
DNGYLIFILW SVAALAAFRV VGSMAFLFMK YLRIIVSYRN KVEGSGSWEV SKLDLPNVFH 960
KKG 964
Keyword

KW-0961--Cell wall biogenesis/degradation
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR004835--Chitin_synth
IPR004834--Chitin_synth_fun
IPR013616--Chitin_synth_N
IPR029044--Nucleotide-diphossugar_trans
PROSITE
Pfam

PF01644--Chitin_synth_1
PF08407--Chitin_synth_1N
Gene Ontology

GO:0005935--C:cellular bud neck
GO:0016021--C:integral component of membrane
GO:0004100--F:chitin synthase activity
GO:0000916--P:actomyosin contractile ring contraction
GO:0071555--P:cell wall organization
GO:0006031--P:chitin biosynthetic process