dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005848
Uniprot Accession P14065; GCY1_YEAST; D6W2H9;
Genbank Protein ID NP_014763.1;
Genbank Nucleotide ID NM_001183539.1;
Protein Name Glycerol 2-dehydrogenase (NADP(+))
Protein Synonyms/Alias Galactose-inducible crystallin-like protein 1;
Gene Name GCY1
Gene Synonyms/Alias GCY;YOR120W;O31567;YOR3269W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
4----MPATLHDSTKIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
172AVGVSNFSINNLKDLcurated22369663; 22817900; 24961812
220GIVVEAYSPLGSTDAcurated24961812
306RVVHPNWSPFEVFK-PhosphoGRID 2.0;UniProt;curated19779198; 22817900
Sequence
(Fasta)
MPATLHDSTK ILSLNTGAQI PQIGLGTWQS KENDAYKAVL TALKDGYRHI DTAAIYRNED 60
QVGQAIKDSG VPREEIFVTT KLWCTQHHEP EVALDQSLKR LGLDYVDLYL MHWPARLDPA 120
YIKNEDILSV PTKKDGSRAV DITNWNFIKT WELMQELPKT GKTKAVGVSN FSINNLKDLL 180
ASQGNKLTPA ANQVEIHPLL PQDELINFCK SKGIVVEAYS PLGSTDAPLL KEPVILEIAK 240
KNNVQPGHVV ISWHVQRGYV VLPKSVNPDR IKTNRKIFTL STEDFEAINN ISKEKGEKRV 300
VHPNWSPFEV FK 313
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0319--Glycerol metabolism
KW-0521--NADP
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR001395--Aldo/ket_red/Kv-b
IPR018170--Aldo/ket_reductase_CS
IPR020471--Aldo/keto_reductase
IPR023210--NADP_OxRdtase_dom

PROSITE

PS00798--ALDOKETO_REDUCTASE_1
PS00062--ALDOKETO_REDUCTASE_2
PS00063--ALDOKETO_REDUCTASE_3

Pfam

PF00248--Aldo_ket_red

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004032--F:alditol:NADP+ 1-oxidoreductase activity
GO:0004033--F:aldo-keto reductase (NADP) activity
GO:0047953--F:glycerol 2-dehydrogenase (NADP+) activity
GO:1990042--F:glycerol dehydrogenase [NAD(P)+] activity
GO:0003729--F:mRNA binding
GO:0016491--F:oxidoreductase activity
GO:0019568--P:arabinose catabolic process
GO:0034599--P:cellular response to oxidative stress
GO:0042843--P:D-xylose catabolic process
GO:0006071--P:glycerol metabolic process