dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005841
Uniprot Accession P14020; DPM1_YEAST; D6W4I3;
Genbank Protein ID NP_015509.1;
Genbank Nucleotide ID NM_001184280.1;
Protein Name Dolichol-phosphate mannosyltransferase
Protein Synonyms/Alias Dolichol-phosphate mannose synthase;DPM synthase;Dolichyl-phosphate beta-D-mannosyltransferase;Mannose-P-dolichol synthase;MPD synthase;
Gene Name DPM1
Gene Synonyms/Alias SED3;YPR183W;P9705.3;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
2------MSIEYSVIVcurated26040406
5---MSIEYSVIVPAYcurated26040406
6--MSIEYSVIVPAYHcurated26040406
141PMYRRVISSTARMMAdbPTM 3.0;PhosphoGRID 2.0-; 16381945; 23193290; 15548536
Sequence
(Fasta)		MSIEYSVIVP AYHEKLNIKP LTTRLFAGMS PEMAKKTELI FVDDNSQDGS VEEVDALAHQ 60
GYNVRIIVRT NERGLSSAVL KGFYEAKGQY LVCMDADLQH PPETVPKLFE SLHDHAFTLG 120
TRYAPGVGID KDWPMYRRVI SSTARMMARP LTIASDPMSG FFGLQKKYLE NCNPRDINSQ 180
GFKIALELLA KLPLPRDPRV AIGEVPFTFG VRTEGESKLS GKVIIQYLQQ LKELYVFKFG 240
ANNLILFITF WSILFFYVCY QLYHLVF 268
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0256--Endoplasmic reticulum
KW-0328--Glycosyltransferase
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001173--Glyco_trans_2-like
IPR029044--Nucleotide-diphossugar_trans
PROSITE
Pfam

PF00535--Glycos_transf_2
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0042175--C:nuclear outer membrane-endoplasmic reticulum membrane network
GO:0004582--F:dolichyl-phosphate beta-D-mannosyltransferase activity
GO:0004169--F:dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0019348--P:dolichol metabolic process
GO:0006488--P:dolichol-linked oligosaccharide biosynthetic process
GO:0006506--P:GPI anchor biosynthetic process
GO:0035269--P:protein O-linked mannosylation