dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005803
Uniprot Accession P13709; FSH_DROME; A4V442; P13710; Q8IRN6; Q9W3L3;
Genbank Protein ID NP_001162699.1; NP_511078.2; NP_727228.1; NP_996368.1; NP_996369.1; NP_996370.1;
Genbank Nucleotide ID NM_001169228.2; NM_078523.3; NM_167144.4; NM_206645.4; NM_206646.4; NM_206647.3;
Protein Name Homeotic protein female sterile
Protein Synonyms/Alias Fragile-chorion membrane protein;
Gene Name fs(1)h
Gene Synonyms/Alias fsh;CG2252;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Required maternally for proper expression of other homeotic genes involved in pattern formation, such as Ubx.
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
452NMSPLGVSGVPGLGGdbPTM 3.0;Phospho.ELM 9.0;UniProt18327897; 16381945; 23193290
943SQVMNFDSEEEDTAKdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
948FDSEEEDTAKPMSYDPHOSIDA;curated21081558; 22817900
1653SSLASANSPQSHTSSdbPTM 3.0;Phospho.ELM 9.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19060867; 19366988; 22817900
1963AMESGRKSVHDAQPQdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
1980RVEDIKASPGGQGQSdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19060867; 19366988;
1988PGGQGQSSPAQQSPQdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSSSEPPPRY EPPVEPVNGI VQPPVIPPAE RPGRNTNQLQ YLIKTVMKVI WKHHFSWPFQ 60
QPVDAKKLNL PDYHKIIKQP MDMGTIKKRL ENNYYWSAKE TIQDFNTMFN NCYVYNKPGE 120
DVVVMAQTLE KVFLQKIESM PKEELELEPV TAKGGKKKQR APATPKSSSG GAGASTGSGT 180
SSAAVTSGPG SGSTKVSVAA SSAQQSGLQG ATGAGGGSSS TPGTQPGSGA GGAIAARPVS 240
AMGGTVSSTA GGAPSIPPIS TMPPHTVPGS TNTTTTAMAG GVGGPGAAGA NPNAAALMAS 300
LLNAGQTGAY PGAPGQTAVN SSSLLDGSTA AVAAAAAAAA AAAAAAGGAA GAAGGAGTIP 360
AVAVNAANAV QAYVNAGVSV GVDAVIPPQQ PAKIKKGVKR KADTTTPTAN AFESPYTQMD 420
SKSAKIATRR ESNRQDLTFQ GSGYNMSPLG VSGVPGLGGL VAGGVAGVAV AKNKEKLSDA 480
LKSCNEILKE LFSKKHSGYA WPFYKPVDAE MLGLHDYHDI IKKPMDLGTV KRKMDNREYK 540
SAPEFAADVR LIFTNCYKYN PPDHDVVAMG RKLQDVFEMR YANIPDEPVA NAAHHHGHGH 600
GHGHGHGHGH GHGHGHGHGH GYGGSSSLKH DASDSSSEDS SDTENESNSD EERSARLKML 660
ESKLLGLQEE IRKLSEEASA KKKAKKKLKE KKKSIGGGSG SGSASHHCHA TGGGANAGGA 720
GGPGSGGHGS VSVPGGVGSL GPGGAGGANL NALLGGSLVG HGGAAVAGGV PNVGALHSQV 780
HDVAMAFSQM AGGGAAAGAG FGAGVTAAGA SSGGKAGTLA GALAAGAAAG AGGTTAGSGS 840
SKGAKSKGGR GAKGSGAGGV GASNNAAAGN AAGGAAGAAA GAGSVGGVGG AGAAGGGNAS 900
KRAKGSSSAG AGGGVGGANA SAGGAGARGS SKKKPSQVMN FDSEEEDTAK PMSYDEKRQL 960
SLDINKLPGD KLGRVVHIIQ NREPSLRDSN PDEIEIDFET LKPSTLRELE SYVASCLRKK 1020
THKKPSGKSK DEQMAEKKQE LEKRLQDVTG QLGASKKTAK KDESASSKVE AVQPANPVSS 1080
SSSSSDSSSS SSSDSSSSDS SDSEAGDGDE RPPRKKKSRD SNGSNVNNPS INVVMGGNLP 1140
SGALSPTTML MGLDHVVNSN TPTSQMSNML GNANPLTAAA MLNNNNKTSL PGSNFGGAPA 1200
PGNMMHAGAG VPVAGAAVSA STGQQHNKNG PNDLSKVQPG GPINAALPPH SFAGGTATVA 1260
TSQSSGGIRI ASNLHKPSGL GGGDLGEHHA ALAAALTSGI NSTGTAGGGI NNNGGSNNNA 1320
NPLGGSHGDA MVNASLASLA SGLKQIPQFD DPVEQSLASL EFSAGSTGKS GLTDNFLMQQ 1380
HLMQPAGPQQ QQQQQQQQPF GHQQQQQQQQ QQQQQQQQHM DYVTELLSKG AENVGGMNGN 1440
HLLNFNLDMA AAYQQKHPQQ QQQQAHNNGF NVADFGMAGF DGLNMTAASF LDLEPSLQQQ 1500
QMQQMQLQQQ HHQQQQQQTH QQQQQHQQQH HQQQQQQQLT QQQLQQQQQQ QQQQQHLQQQ 1560
QHQQQHHQAA NKLLIIPKPI ESMMPSPPDK QQLQQHQKVL PPQQSPSDMK LHPNAAAAAA 1620
VASAQAKLVQ TFKANEQNLK NASSWSSLAS ANSPQSHTSS SSSSSKAKPA MDSFQQFRNK 1680
AKERDRLKLL EAAEKEKKNQ KEAAEKEQQR KHHKSSSSSL TSAAVAQAAA IAAATAAAAV 1740
TLGAAAAAAL ASSASNPSGG SSSGGAGSTS QQAITGDRDR DRDRERERER SGSGGGQSGN 1800
GNNSSNSANS NGPGSAGSGG SGGGGGSGPA SAGGPNSGGG GTANSNSGGG GGGGGPALLN 1860
AGSNSNSGVG SGGAASSNSN SSVGGIVGSG GPGSNSQGSS GGGGGGPASG GGMGSGAIDY 1920
GQQVAVLTQV AANAQAQHVA AAVAAQAILA ASPLGAMESG RKSVHDAQPQ ISRVEDIKAS 1980
PGGQGQSSPA QQSPQDRAAA KRAEQRRAEQ ERRRREALAG QIDMNMQSDL MAAFEETL 2039
Keyword

KW-0025--Alternative splicing
KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR031354--BRD4_CDT
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR027353--NET_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51525--NET

Pfam

PF17035--BET
PF17105--BRD4_CDT
PF00439--Bromodomain

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0007476--P:imaginal disc-derived wing morphogenesis
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0007362--P:terminal region determination