Tag |
Content |
dbPAF ID |
dbPAF-0005778 |
Uniprot Accession |
P13607; ATNA_DROME; A4V366; A4V367; O61494; Q0KI37; Q7KS94; Q7KS95; Q86MY6; Q86MY7; Q86MY8; Q86MY9; Q86MZ0; Q8IN40; Q8T0L8; Q9VDG6; Q9VDG7; Q9VDG8;
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Genbank Protein ID |
NP_001262790.1; NP_001262791.1; NP_732572.1; NP_732573.1; NP_732574.1; NP_732575.1; NP_996247.1; NP_996248.1; NP_996249.1; NP_996250.1;
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Genbank Nucleotide ID |
NM_001275861.1; NM_001275862.2; NM_169936.3; NM_169937.3; NM_169938.3; NM_169939.2; NM_206525.3; NM_206526.3; NM_206527.3; NM_206528.3;
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Protein Name |
Sodium/potassium-transporting ATPase subunit alpha |
Protein Synonyms/Alias |
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Gene Name |
Atpalpha |
Gene Synonyms/Alias |
Na-p;CG5670; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Functional Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
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Phosphorylation Sites
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dbPAF PTMs: 5 |
Sequence (Fasta) | MALRSDYEHG RADSYRVATV IATDDDNRTA DGQYKSRRKM PAKVNKKENL DDLKQELDID 60 FHKISPEELY QRFQTHPENG LSHAKAKENL ERDGPNALTP PKQTPEWVKF CKNLFGGFAM 120 LLWIGAILCF VAYSIQASTS EEPADDNLYL GIVLSAVVIV TGIFSYYQES KSSKIMESFK 180 NMVPQFATVI REGEKLTLRA EDLVLGDVVE VKFGDRIPAD IRIIEARNFK VDNSSLTGES 240 EPQSRGAEFT HENPLETKNL AFFSTNAVEG TAKGVVISCG DHTVMGRIAG LASGLDTGET 300 PIAKEIHHFI HLITGVAVFL GVTFFVIAFI LGYHWLDAVI FLIGIIVANV PEGLLATVTV 360 CLTLTAKRMA SKNCLVKNLE AVETLGSTST ICSDKTGTLT QNRMTVAHMW FDNQIIEADT 420 TEDQSGVQYD RTSPGFKALS RIATLCNRAE FKGGQDGVPI LKKEVSGDAS EAALLKCMEL 480 ALGDVMNIRK RNKKIAEVPF NSTNKYQVSI HETEDTNDPR YLLVMKGAPE RILERCSTIF 540 INGKEKVLDE EMKEAFNNAY MELGGLGERV LGFCDFMLPS DKYPNGFKFN TDDINFPIDN 600 LRFVGLMSMI DPPRAAVPDA VAKCRSAGIK VIMVTGDHPI TAKAIAKSVG IISEGNETVE 660 DIAQRLNIPV SEVNPREAKA AVVHGAELRD VSSDQLDEIL RYHTEIVFAR TSPQQKLIIV 720 EGCQRMGAIV AVTGDGVNDS PALKKADIGV AMGIAGSDVS KQAADMILLD DNFASIVTGV 780 EEGRLIFDNL KKSIAYTLTS NIPEISPFLA FILCDIPLPL GTVTILCIDL GTDMVPAISL 840 AYEHAEADIM KRPPRDPFND KLVNSRLISM AYGQIGMIQA AAGFFVYFVI MAENGFLPKK 900 LFGIRKMWDS KAVNDLTDSY GQEWTYRDRK TLEYTCHTAF FISIVVVQWA DLIICKTRRN 960 SIFQQGMRNW ALNFGLVFET VLAAFLSYCP GMEKGLRMYP LKLVWWFPAI PFALAIFIYD 1020 ETRRFYLRRN PGGWLEQETY Y
1042Fasta Sequence
>P13607|Atpalpha|Drosophila melanogaster(Fruit fly) MALRSDYEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY
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Keyword |
KW-0025--Alternative splicing KW-0067--ATP-binding KW-0181--Complete proteome KW-0378--Hydrolase KW-0406--Ion transport KW-0472--Membrane KW-0547--Nucleotide-binding KW-0597--Phosphoprotein KW-0630--Potassium KW-0633--Potassium transport KW-1185--Reference proteome KW-0691--RNA editing KW-0915--Sodium KW-0739--Sodium transport KW-0740--Sodium/potassium transport KW-0812--Transmembrane KW-1133--Transmembrane helix KW-0813--Transport
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Interpro |
IPR006068--ATPase_P-typ_cation-transptr_C IPR004014--ATPase_P-typ_cation-transptr_N IPR023299--ATPase_P-typ_cyto_domN IPR018303--ATPase_P-typ_P_site IPR023298--ATPase_P-typ_TM_dom IPR008250--ATPase_P-typ_transduc_dom_A IPR023214--HAD-like_dom IPR005775--P-type_ATPase_IIC IPR001757--P_typ_ATPase
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PROSITE |
PS00154--ATPASE_E1_E2
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Pfam |
PF00689--Cation_ATPase_C PF00690--Cation_ATPase_N PF00122--E1-E2_ATPase
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Gene Ontology |
GO:0016323--C:basolateral plasma membrane GO:0005737--C:cytoplasm GO:0005887--C:integral component of plasma membrane GO:0005634--C:nucleus GO:0005886--C:plasma membrane GO:0005918--C:septate junction GO:0005890--C:sodium:potassium-exchanging ATPase complex GO:0005524--F:ATP binding GO:0046872--F:metal ion binding GO:0005391--F:sodium:potassium-exchanging ATPase activity GO:0008344--P:adult locomotory behavior GO:0015991--P:ATP hydrolysis coupled proton transport GO:0006812--P:cation transport GO:0030007--P:cellular potassium ion homeostasis GO:0006883--P:cellular sodium ion homeostasis GO:0008340--P:determination of adult lifespan GO:0001700--P:embryonic development via the syncytial blastoderm GO:0007630--P:jump response GO:0007626--P:locomotory behavior GO:0050905--P:neuromuscular process GO:0010107--P:potassium ion import GO:0008360--P:regulation of cell shape GO:0035152--P:regulation of tube architecture, open tracheal system GO:0035158--P:regulation of tube diameter, open tracheal system GO:0035159--P:regulation of tube length, open tracheal system GO:0009612--P:response to mechanical stimulus GO:0009266--P:response to temperature stimulus GO:0007605--P:sensory perception of sound GO:0019991--P:septate junction assembly GO:0036376--P:sodium ion export from cell GO:0051124--P:synaptic growth at neuromuscular junction GO:0007268--P:synaptic transmission GO:0001894--P:tissue homeostasis GO:0060439--P:trachea morphogenesis
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