| Tag |
Content |
| dbPAF ID |
dbPAF-0005770 |
| Uniprot Accession |
P13587; ATN1_YEAST; D6VS28;
|
| Genbank Protein ID |
NP_010325.1;
|
| Genbank Nucleotide ID |
NM_001180348.1;
|
| Protein Name |
Sodium transport ATPase 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
ENA1 |
| Gene Synonyms/Alias |
HOR6;PMR2;PMR2A;YDR040C;YD6888.02C; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the sodium or lithium ions to allow salt tolerance. Is negatively modulated by SIS2/HAL3.Functional Description
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the sodium or lithium ions to allow salt tolerance. Is negatively modulated by SIS2/HAL3. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MGEGTTKENN NAEFNAYHTL TAEEAAEFIG TSLTEGLTQD EFVHRLKTVG ENTLGDDTKI 60
DYKAMVLHQV CNAMIMVLLI SMIISFAMHD WITGGVISFV IAVNVLIGLV QEYKATKTMN 120
SLKNLSSPNA HVIRNGKSET INSKDVVPGD ICLVKVGDTI PADLRLIETK NFDTDESLLT 180
GESLPVSKDA NLVFGKEEET SVGDRLNLAF SSSAVVKGRA KGIVIKTALN SEIGKIAKSL 240
QGDSGLISRD PSKSWLQNTW ISTKKVTGAF LGTNVGTPLH RKLSKLAVLL FWIAVLFAII 300
VMASQKFDVD KRVAIYAICV ALSMIPSSLV VVLTITMSVG AAVMVSRNVI VRKLDSLEAL 360
GAVNDICSDK TGTLTQGKML ARQIWIPRFG TITISNSDDP FNPNEGNVSL IPRFSPYEYS 420
HNEDGDVGIL QNFKDRLYEK DLPEDIDMDL FQKWLETATL ANIATVFKDD ATDCWKAHGD 480
PTEIAIQVFA TKMDLPHNAL TGEKSTNQSN ENDQSSLSQH NEKPGSAQFE HIAEFPFDST 540
VKRMSSVYYN NHNETYNIYG KGAFESIISC CSSWYGKDGV KITPLTDCDV ETIRKNVYSL 600
SNEGLRVLGF ASKSFTKDQV NDDQLKNITS NRATAESDLV FLGLIGIYDP PRNETAGAVK 660
KFHQAGINVH MLTGDFVGTA KAIAQEVGIL PTNLYHYSQE IVDSMVMTGS QFDGLSEEEV 720
DDLPVLPLVI ARCSPQTKVR MIEALHRRKK FCTMTGDGVN DSPSLKMANV GIAMGINGSD 780
VSKEASDIVL SDDNFASILN AVEEGRRMTD NIQKFVLQLL AENVAQALYL IIGLVFRDEN 840
GKSVFPLSPV EVLWIIVVTS CFPAMGLGLE KAAPDLMDRP PHDSEVGIFT WEVIIDTFAY 900
GIIMTGSCMA SFTGSLYGIN SGRLGHDCDG TYNSSCRDVY RSRSAAFATM TWCALILAWE 960
VVDMRRSFFR MHPDTDSPVK EFFRSIWGNQ FLFWSIIFGF VSAFPVVYIP VINDKVFLHK 1020
PIGAEWGLAI AFTIAFWIGA ELYKCGKRRY FKTQRAHNPE NDLESNNKRD PFEAYSTSTT 1080
IHTEVNIGIK Q
1092Fasta Sequence
>P13587|ENA1|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MGEGTTKENNNAEFNAYHTLTAEEAAEFIGTSLTEGLTQDEFVHRLKTVGENTLGDDTKIDYKAMVLHQVCNAMIMVLLISMIISFAMHDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPNAHVIRNGKSETINSKDVVPGDICLVKVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDANLVFGKEEETSVGDRLNLAFSSSAVVKGRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSKSWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDKRVAIYAICVALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKMLARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHNEDGDVGILQNFKDRLYEKDLPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMDLPHNALTGEKSTNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMSSVYYNNHNETYNIYGKGAFESIISCCSSWYGKDGVKITPLTDCDVETIRKNVYSLSNEGLRVLGFASKSFTKDQVNDDQLKNITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCTMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNIQKFVLQLLAENVAQALYLIIGLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAPDLMDRPPHDSEVGIFTWEVIIDTFAYGIIMTGSCMASFTGSLYGINSGRLGHDCDGTYNSSCRDVYRSRSAAFATMTWCALILAWEVVDMRRSFFRMHPDTDSPVKEFFRSIWGNQFLFWSIIFGFVSAFPVVYIPVINDKVFLHKPIGAEWGLAIAFTIAFWIGAELYKCGKRRYFKTQRAHNPENDLESNNKRDPFEAYSTSTTIHTEVNIGIKQ
|
| Keyword |
KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0406--Ion transport
KW-0460--Magnesium
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0915--Sodium
KW-0739--Sodium transport
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
|
| Interpro |
IPR006068--ATPase_P-typ_cation-transptr_C
IPR004014--ATPase_P-typ_cation-transptr_N
IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR023298--ATPase_P-typ_TM_dom
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006414--P-type_ATPase_IID
IPR001757--P_typ_ATPase
|
| PROSITE |
PS00154--ATPASE_E1_E2
|
| Pfam |
PF00689--Cation_ATPase_C
PF00690--Cation_ATPase_N
PF00122--E1-E2_ATPase
PF00702--Hydrolase
|
| Gene Ontology |
GO:0005887--C:integral component of plasma membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0008556--F:potassium-transporting ATPase activity
GO:0008554--F:sodium-exporting ATPase activity, phosphorylative mechanism
GO:0098655--P:cation transmembrane transport
GO:0042149--P:cellular response to glucose starvation
GO:0006972--P:hyperosmotic response
GO:0071805--P:potassium ion transmembrane transport
GO:0006813--P:potassium ion transport
GO:0009268--P:response to pH
GO:0009651--P:response to salt stress
GO:0035725--P:sodium ion transmembrane transport
GO:0006814--P:sodium ion transport
GO:0055085--P:transmembrane transport
|
