dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005769
Uniprot Accession P13586; ATC1_YEAST; D6VTY5;
Genbank Protein ID NP_011348.1;
Genbank Nucleotide ID NM_001181032.1;
Protein Name Calcium-transporting ATPase 1
Protein Synonyms/Alias Bypass SOD defects protein 1;Golgi Ca(2+)-ATPase;
Gene Name PMR1
Gene Synonyms/Alias BSD1;SCC1;YGL167C;G1666;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Has a role in the secretory pathway.
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
15ASLLDEDSNREREILcurated22369663
227SFNDQPNSIVPISERPhosphoGRID 2.0;UniProt;curated19779198; 22817900
373NVICSDKTGTLTSNHcurated19823750
377SDKTGTLTSNHMTVSPhosphoGRID 2.0;curated19823750; 19795423
382TLTSNHMTVSKLWCLcurated19823750
384TSNHMTVSKLWCLDScurated19823750
539TINECANSMASEGLRcurated22817900; 19547744
542ECANSMASEGLRVFGcurated22817900; 19547744
Sequence
(Fasta)
MSDNPFNASL LDEDSNRERE ILDATAEALS KPSPSLEYCT LSVDEALEKL DTDKNGGLRS 60
SNEANNRRSL YGPNEITVED DESLFKKFLS NFIEDRMILL LIGSAVVSLF MGNIDDAVSI 120
TLAIFIVVTV GFVQEYRSEK SLEALNKLVP AECHLMRCGQ ESHVLASTLV PGDLVHFRIG 180
DRIPADIRII EAIDLSIDES NLTGENEPVH KTSQTIEKSS FNDQPNSIVP ISERSCIAYM 240
GTLVKEGHGK GIVVGTGTNT SFGAVFEMMN NIEKPKTPLQ LTMDKLGKDL SLVSFIVIGM 300
ICLVGIIQGR SWLEMFQISV SLAVAAIPEG LPIIVTVTLA LGVLRMAKRK AIVRRLPSVE 360
TLGSVNVICS DKTGTLTSNH MTVSKLWCLD SMSNKLNVLS LDKNKKTKNS NGNLKNYLTE 420
DVRETLTIGN LCNNASFSQE HAIFLGNPTD VALLEQLANF EMPDIRNTVQ KVQELPFNSK 480
RKLMATKILN PVDNKCTVYV KGAFERILEY STSYLKSKGK KTEKLTEAQK ATINECANSM 540
ASEGLRVFGF AKLTLSDSST PLTEDLIKDL TFTGLIGMND PPRPNVKFAI EQLLQGGVHI 600
IMITGDSENT AVNIAKQIGI PVIDPKLSVL SGDKLDEMSD DQLANVIDHV NIFARATPEH 660
KLNIVRALRK RGDVVAMTGD GVNDAPALKL SDIGVSMGRI GTDVAKEASD MVLTDDDFST 720
ILTAIEEGKG IFNNIQNFLT FQLSTSVAAL SLVALSTAFK LPNPLNAMQI LWINILMDGP 780
PAQSLGVEPV DHEVMKKPPR KRTDKILTHD VMKRLLTTAA CIIVGTVYIF VKEMAEDGKV 840
TARDTTMTFT CFVFFDMFNA LACRHNTKSI FEIGFFTNKM FNYAVGLSLL GQMCAIYIPF 900
FQSIFKTEKL GISDILLLLL ISSSVFIVDE LRKLWTRKKN EEDSTYFSNV 951
Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0106--Calcium
KW-0109--Calcium transport
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0406--Ion transport
KW-0460--Magnesium
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport

Interpro

IPR006068--ATPase_P-typ_cation-transptr_C
IPR004014--ATPase_P-typ_cation-transptr_N
IPR023299--ATPase_P-typ_cyto_domN
IPR018303--ATPase_P-typ_P_site
IPR023298--ATPase_P-typ_TM_dom
IPR008250--ATPase_P-typ_transduc_dom_A
IPR023214--HAD-like_dom
IPR006413--P-type_ATPase_IIA_PMR1
IPR001757--P_typ_ATPase

PROSITE

PS00154--ATPASE_E1_E2

Pfam

PF00689--Cation_ATPase_C
PF00690--Cation_ATPase_N
PF00122--E1-E2_ATPase
PF00702--Hydrolase

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0000139--C:Golgi membrane
GO:0005887--C:integral component of plasma membrane
GO:0005524--F:ATP binding
GO:0005509--F:calcium ion binding
GO:0005388--F:calcium-transporting ATPase activity
GO:0015410--F:manganese-transporting ATPase activity
GO:0070588--P:calcium ion transmembrane transport
GO:0006816--P:calcium ion transport
GO:0006874--P:cellular calcium ion homeostasis
GO:0006887--P:exocytosis
GO:0016236--P:macroautophagy
GO:0071421--P:manganese ion transmembrane transport
GO:0006828--P:manganese ion transport