dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005760
Uniprot Accession P13517; CAPZB_YEAST; D6VVP8; Q07082;
Genbank Protein ID NP_012230.3;
Genbank Nucleotide ID NM_001179384.3;
Protein Name F-actin-capping protein subunit beta
Protein Synonyms/Alias
Gene Name CAP2
Gene Synonyms/Alias YIL034C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
2------MSDAQFDAAcurated22369663
74RDIDSFRSPWSNTYYPhosphoGRID 2.019779198
85NTYYPELSPKDLQDSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 18407956; 16381945; 23193290; 19060867; 19366988;
92SPKDLQDSPFPSAPLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900;
267TKNAAIASSAEEANKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 19366988; 22369663
268KNAAIASSAEEANKDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 24961812
286EVIRGLQSL------PhosphoGRID 2.0;curated19823750; 19795423; 25521595
Sequence
(Fasta)		MSDAQFDAAL DLLRRLNPTT LQENLNNLIE LQPNLAQDLL SSVDVPLSTQ KDSADSNREY 60
LCCDYNRDID SFRSPWSNTY YPELSPKDLQ DSPFPSAPLR KLEILANDSF DVYRDLYYEG 120
GISSVYLWDL NEEDFNGHDF AGVVLFKKNQ SDHSNWDSIH VFEVTTSPSS PDSFNYRVTT 180
TIILHLDKTK TDQNSHMMLS GNLTRQTEKD IAIDMSRPLD VIFTSHVANL GSLIEDIESQ 240
MRNLLETVYF EKTRDIFHQT KNAAIASSAE EANKDAQAEV IRGLQSL 288
Keyword

KW-0007--Acetylation
KW-0117--Actin capping
KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR001698--CAPZB
IPR019771--F-actin_capping_bsu_CS
PROSITE

PS00231--F_ACTIN_CAPPING_BETA
Pfam

PF01115--F_actin_cap_B
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0005884--C:actin filament
GO:0005934--C:cellular bud tip
GO:0008290--C:F-actin capping protein complex
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0051016--P:barbed-end actin filament capping
GO:0000902--P:cell morphogenesis
GO:0030447--P:filamentous growth