dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0005750
Uniprot Accession P13469; MODU_DROME; Q9V9S2;
Genbank Protein ID NP_001247401.1; NP_524614.2;
Genbank Nucleotide ID NM_001260472.2; NM_079875.3;
Protein Name DNA-binding protein modulo
Protein Synonyms/Alias
Gene Name mod
Gene Synonyms/Alias CG2050;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Its capacity to bind DNA and protein(s), and its differential expression during development suggest a role in the regulation of gene expression during Drosophila development. It could, in interaction with other factors, be required for the translation of instructions provided by pattern forming genes and controls, via chromatin changes, the activity of genes critical for the process of morphogenesis of several embryonic territories.
Phosphorylation Sites
dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
27KPLAKRVTKSTKVQEcurated22817900
42EETVVPQSPSKKSRKdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17372656; 18327897; 16381945; 23193290; 21081558; 19060867;
44TVVPQSPSKKSRKQPdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17372656; 18327897; 16381945; 23193290; 21081558; 19060867;
101EEDEEYNSDDEEDDDcurated22817900
120EPGEVSKSEGADEVDdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 21081558; 19366988; 22817900
129GADEVDESDDDEEAPdbPTM 3.0;Phospho.ELM 9.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17372656; 18327897; 16381945; 23193290; 21081558; 19060867;
142APVEKPVSKKSEKANdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
150KKSEKANSEKSEENRPHOSIDA;curated21081558; 22817900
153EKANSEKSEENRGIPPHOSIDA21081558
304RAFVRLASVDDIPKAdbPTM 3.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17372656; 16381945; 23193290; 18327897; 21081558; 19060867;
443LRKVFNDSGEIESIIdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MAQKKAVTVK GKKATNGEEK PLAKRVTKST KVQEEETVVP QSPSKKSRKQ PVKEVPQFSE 60
EDESDVEEQN DEQPGDDSDF ETEEAAGLID DEAEEDEEYN SDDEEDDDDD ELEPGEVSKS 120
EGADEVDESD DDEEAPVEKP VSKKSEKANS EKSEENRGIP KVKVGKIPLG TPKNQIVFVT 180
NLPNEYLHKD LVALFAKFGR LSALQRFTNL NGNKSVLIAF DTSTGAEAVL QAKPKALTLG 240
DNVLSVSQPR NKEENNERTV VVGLIGPNIT KDDLKTFFEK VAPVEAVTIS SNRLMPRAFV 300
RLASVDDIPK ALKLHSTELF SRFITVRRIS QESISRTSEL TLVVENVGKH ESYSSDALEK 360
IFKKFGDVEE IDVVCSKAVL AFVTFKQSDA ATKALAQLDG KTVNKFEWKL HRFERSTSGR 420
AILVTNLTSD ATEADLRKVF NDSGEIESII MLGQKAVVKF KDDEGFCKSF LANESIVNNA 480
PIFIEPNSLL KHRLLKKRLA IGQTRAPRKF QKDTKPNFGK KPFNKRPAQE NGGKSFVKRA 540
RF 543
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0694--RNA-binding

Interpro

IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom

PROSITE

PS50102--RRM

Pfam

PF00076--RRM_1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0003677--F:DNA binding
GO:0003729--F:mRNA binding
GO:0000166--F:nucleotide binding
GO:0043565--F:sequence-specific DNA binding
GO:0008283--P:cell proliferation
GO:0007286--P:spermatid development