dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005726
Uniprot Accession P13259; PCY1_YEAST; D6VUY4;
Genbank Protein ID NP_011718.1;
Genbank Nucleotide ID NM_001181331.1;
Protein Name Choline-phosphate cytidylyltransferase
Protein Synonyms/Alias CTP:phosphocholine cytidylyltransferase;CCT;CT;Phosphorylcholine transferase;
Gene Name PCT1
Gene Synonyms/Alias CCT;CCT1;YGR202C;G7729;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
9ANPTTGKSSIRAKLSPhosphoGRID 2.0;curated19823750; 19795423
10NPTTGKSSIRAKLSNcurated19823750
16SSIRAKLSNSSLSNLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 21126336;
18IRAKLSNSSLSNLFKdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 21081558; 19366988;
19RAKLSNSSLSNLFKKdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 20702584; 19779198;
21KLSNSSLSNLFKKNKcurated22369663; 20377248
59ENKDTQLTPRKRRRLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 20702584;
220KEMGKFLTTQRTNGVcurated23825934
221EMGKFLTTQRTNGVScurated23825934
346RKLIREASPATEFANdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 18407956; 16381945; 23193290; 17330950; 21177495;
349IREASPATEFANEFTPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 19060867; 26040406; 22369663; 22817900; 24961812;
Sequence
(Fasta)		MANPTTGKSS IRAKLSNSSL SNLFKKNKNK RQREETEEQD NEDKDESKNQ DENKDTQLTP 60
RKRRRLTKEF EEKEARYTNE LPKELRKYRP KGFRFNLPPT DRPIRIYADG VFDLFHLGHM 120
KQLEQCKKAF PNVTLIVGVP SDKITHKLKG LTVLTDKQRC ETLTHCRWVD EVVPNAPWCV 180
TPEFLLEHKI DYVAHDDIPY VSADSDDIYK PIKEMGKFLT TQRTNGVSTS DIITKIIRDY 240
DKYLMRNFAR GATRQELNVS WLKKNELEFK KHINEFRSYF KKNQTNLNNA SRDLYFEVRE 300
ILLKKTLGKK LYSKLIGNEL KKQNQRQRKQ NFLDDPFTRK LIREASPATE FANEFTGENS 360
TAKSPDDNGN LFSQEDDEDT NSNNTNTNSD SDSNTNSTPP SEDDDDNDRL TLENLTQKKK 420
QSAN 425
Keyword

KW-0181--Complete proteome
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0472--Membrane
KW-0548--Nucleotidyltransferase
KW-0594--Phospholipid biosynthesis
KW-1208--Phospholipid metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR004821--Cyt_trans-like
IPR014729--Rossmann-like_a/b/a_fold
PROSITE
Pfam

PF01467--CTP_transf_like
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016020--C:membrane
GO:0005635--C:nuclear envelope
GO:0005634--C:nucleus
GO:0004105--F:choline-phosphate cytidylyltransferase activity
GO:0006657--P:CDP-choline pathway
GO:0006656--P:phosphatidylcholine biosynthetic process