dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0005716
Uniprot Accession P13185; KIN1_YEAST; D6VSA8; Q04606;
Genbank Protein ID NP_010407.1;
Genbank Nucleotide ID NM_001180430.1;
Protein Name Serine/threonine protein kinase KIN1
Protein Synonyms/Alias
Gene Name KIN1
Gene Synonyms/Alias YDR122W;YD9727.17;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Serine/threonine protein kinase involved in the regulation of exocytosis. Induces phosphorylation of SEC9 and its release from the plasma membrane to the cytosol.
Phosphorylation Sites
 dbPAF PTMs: 55 (View all)
PositionPeptidesSourceReferences ( PMIDs )
23NQQDDGNSESNSMHTdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 19060867; 19366988;
25QDDGNSESNSMHTQPPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 26040406; 22817900
27DGNSESNSMHTQPSTdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040406;
30SESNSMHTQPSTMAPPhosphoGRID 2.0;curated19779198; 22817900; 25315811
46TLRMMGKSPQQQQQQPhosphoGRID 2.0;PhosphoPep 2.0;curated20489023; 19060867; 25521595; 24961812; 25315811
103TTSQSRVSSSQGMPKPhosphoGRID 2.0;curated20489023; 25315811
104TSQSRVSSSQGMPKQPhosphoGRID 2.0;curated20489023; 25315811
302DSRKQLHTFCGSLYFdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900;
521RNQQQRQSHENIEKLdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 17563356; 16381945; 23193290; 19823750; 19795423;
534KLSEIPESVKQRDVEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900;
561TLATKDTSVPFTPKNPhosphoGRID 2.0;curated19779198; 22817900
592AMPEQAHTSPTSRKSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20702584; 19060867; 19366988;
593MPEQAHTSPTSRKSSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 19779198;
595EQAHTSPTSRKSSDNPhosphoPep 2.0;curated19060867; 22817900; 25315811
596QAHTSPTSRKSSDNQPhosphoGRID 2.0;PhosphoPep 2.0;curated20702584; 19779198; 19060867; 26040289; 25315811
599TSPTSRKSSDNQRREPhosphoPep 2.0;curated19060867; 24961812; 20377248
612REMEYALSPTPQGNDPhosphoGRID 2.0;curated20489023; 26040289; 24961812; 25315811
614MEYALSPTPQGNDYQcurated26040289
627YQQFRVPSTTGDPSEcurated25315811
646GNIFRKLSQRRKKTIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MDDYHVNTAF SMGRGNQQDD GNSESNSMHT QPSTMAPATL RMMGKSPQQQ QQQNTPLMPP 60
ADIKYANNGN SHQAEQKERQ VELEGKSREN APKPNTTSQS RVSSSQGMPK QFHRKSLGDW 120
EFVETVGAGS MGKVKLAKHR YTNEVCAVKI VNRATKAFLH KEQMLPPPKN EQDVLERQKK 180
LEKEISRDKR TIREASLGQI LYHPHICRLF EMCTLSNHFY MLFEYVSGGQ LLDYIIQHGS 240
IREHQARKFA RGIASALIYL HANNIVHRDL KIENIMISDS SEIKIIDFGL SNIYDSRKQL 300
HTFCGSLYFA APELLKANPY TGPEVDVWSF GVVLFVLVCG KVPFDDENSS VLHEKIKQGK 360
VEYPQHLSIE VISLLSKMLV VDPKRRATLK QVVEHHWMVR GFNGPPPSYL PKRVPLTIEM 420
LDINVLKEMY RLEFIDDVEE TRSVLVSIIT DPTYVLLSRQ YWTLAAKMNA ESSDNGNAPN 480
ITESFEDPTR AYHPMISIYY LTSEMLDRKH AKIRNQQQRQ SHENIEKLSE IPESVKQRDV 540
EVNTTAMKSE PEATLATKDT SVPFTPKNSD GTEPPLHVLI PPRLAMPEQA HTSPTSRKSS 600
DNQRREMEYA LSPTPQGNDY QQFRVPSTTG DPSEKAKFGN IFRKLSQRRK KTIEQTSVNS 660
NNSINKPVQK THSRAVSDFV PGFAKPSYDS NYTMNEPVKT NDSRGGNKGD FPALPADAEN 720
MVEKQREKQI EEDIMKLHDI NKQNNEVAKG SGREAYAAQK FEGSDDDENH PLPPLNVAKG 780
RKLHPSARAK SVGHARRESL KYMRPPMPSS AYPQQELIDT GFLESSDDNK SDSLGNVTSQ 840
TNDSVSVHSV NAHINSPSVE KELTDEEILQ EASRAPAGSM PSIDFPRSLF LKGFFSVQTT 900
SSKPLPIVRY KIMFVLRKMN IEFKEVKGGF VCMQRFSSNN VAAKREGTPR SIMPLSHHES 960
IRRQGSNKYS PSSPLTTNSI HQRKTSITET YGDDKHSGTS LENIHQQGDG SEGMTTTEKE 1020
PIKFEIHIVK VRIVGLAGVH FKKISGNTWL YKELASSILK ELKL 1065
Keyword

KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0268--Exocytosis
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF02149--KA1
PF00069--Pkinase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0006887--P:exocytosis
GO:0035556--P:intracellular signal transduction
GO:0046777--P:protein autophosphorylation
GO:0006468--P:protein phosphorylation