| Tag |
Content |
| dbPAF ID |
dbPAF-0005713 |
| Uniprot Accession |
P13134; KEX2_YEAST; D6W0V5;
|
| Genbank Protein ID |
NP_014161.1;
|
| Genbank Nucleotide ID |
NM_001183076.1;
|
| Protein Name |
Kexin |
| Protein Synonyms/Alias |
Protease KEX2;Proteinase YSCF; |
| Gene Name |
KEX2 |
| Gene Synonyms/Alias |
QDS1;YNL238W;N1122; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Processing of precursors of alpha-factors and killer toxin.Functional Description
Processing of precursors of alpha-factors and killer toxin. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 797 | DANAESASNKLQELQ | curated | 25315811 |
|
Sequence
(Fasta) | MKVRKYITLC FWWAFSTSAL VSSQQIPLKD HTSRQYFAVE SNETLSRLEE MHPNWKYEHD 60
VRGLPNHYVF SKELLKLGKR SSLEELQGDN NDHILSVHDL FPRNDLFKRL PVPAPPMDSS 120
LLPVKEAEDK LSINDPLFER QWHLVNPSFP GSDINVLDLW YNNITGAGVV AAIVDDGLDY 180
ENEDLKDNFC AEGSWDFNDN TNLPKPRLSD DYHGTRCAGE IAAKKGNNFC GVGVGYNAKI 240
SGIRILSGDI TTEDEAASLI YGLDVNDIYS CSWGPADDGR HLQGPSDLVK KALVKGVTEG 300
RDSKGAIYVF ASGNGGTRGD NCNYDGYTNS IYSITIGAID HKDLHPPYSE GCSAVMAVTY 360
SSGSGEYIHS SDINGRCSNS HGGTSAAAPL AAGVYTLLLE ANPNLTWRDV QYLSILSAVG 420
LEKNADGDWR DSAMGKKYSH RYGFGKIDAH KLIEMSKTWE NVNAQTWFYL PTLYVSQSTN 480
STEETLESVI TISEKSLQDA NFKRIEHVTV TVDIDTEIRG TTTVDLISPA GIISNLGVVR 540
PRDVSSEGFK DWTFMSVAHW GENGVGDWKI KVKTTENGHR IDFHSWRLKL FGESIDSSKT 600
ETFVFGNDKE EVEPAATEST VSQYSASSTS ISISATSTSS ISIGVETSAI PQTTTASTDP 660
DSDPNTPKKL SSPRQAMHYF LTIFLIGATF LVLYFMFFMK SRRRIRRSRA ETYEFDIIDT 720
DSEYDSTLDN GTSGITEPEE VEDFDFDLSD EDHLASLSSS ENGDAEHTID SVLTNENPFS 780
DPIKQKFPND ANAESASNKL QELQPDVPPS SGRS
815Fasta Sequence
>P13134|KEX2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGHRIDFHSWRLKLFGESIDSSKTETFVFGNDKEEVEPAATESTVSQYSASSTSISISATSTSSISIGVETSAIPQTTTASTDPDSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS
|
| Keyword |
KW-0002--3D-structure
KW-0106--Calcium
KW-0165--Cleavage on pair of basic residues
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0720--Serine protease
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0865--Zymogen
|
| Interpro |
IPR008979--Galactose-bd-like
IPR000209--Peptidase_S8/S53_dom
IPR023827--Peptidase_S8_Asp-AS
IPR022398--Peptidase_S8_His-AS
IPR023828--Peptidase_S8_Ser-AS
IPR015500--Peptidase_S8_subtilisin-rel
IPR002884--PrprotnconvertsP
|
| PROSITE |
PS00136--SUBTILASE_ASP
PS00137--SUBTILASE_HIS
PS00138--SUBTILASE_SER
|
| Pfam |
PF01483--P_proprotein
PF00082--Peptidase_S8
|
| Gene Ontology |
GO:0016021--C:integral component of membrane
GO:0005802--C:trans-Golgi network
GO:0046872--F:metal ion binding
GO:0004252--F:serine-type endopeptidase activity
GO:0007323--P:peptide pheromone maturation
GO:0016485--P:protein processing
|
