| Tag |
Content |
| dbPAF ID |
dbPAF-0005702 |
| Uniprot Accession |
P13055; E75BB_DROME; Q9VVM9;
|
| Genbank Protein ID |
NP_001246821.1; NP_001246822.1; NP_730321.1;
|
| Genbank Nucleotide ID |
NM_001259892.1; NM_001259893.2; NM_168755.1;
|
| Protein Name |
Ecdysone-induced protein 75B, isoform B |
| Protein Synonyms/Alias |
E75-C;Nuclear receptor subfamily 1 group D member 3, isoform B; |
| Gene Name |
Eip75B |
| Gene Synonyms/Alias |
NR1D3;CG8127; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.Functional Description
Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone. |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MEAVQAAAAA TSSGGSSGSV PGSGSGSASK LIKTEPIDFE MLHLEENERQ QDIEREPSSS 60
NSNSNSNSLT PQRYTHVQVQ TVPPRQPTGL TTPGGTQKVI LTPRVEYVQQ RATSSTGGGM 120
KHVYSQQQGT AASRSAPPET TALLTTTSGT PQIIITRTLP SNQHLSRRHS ASPSALHHYQ 180
QQQPQRQQSP PPLHHQQQQQ QQHVRVIRDG RLYDEATVVV AARRHSVSPP PLHHHSRSAP 240
VSPVIARRGG AAAYMDQQYQ QRQTPPLAPP PPPPPPPPPP PPPQQQQQQY ISTGVPPPTA 300
AARKFVVSTS TRHVNVIASN HFQQQQQQHQ AQQHQQQHQQ HQQHQQHVIA SVSSSSSSSA 360
IGSGGSSSSH IFRTPVVSSS SSSNMHHQQQ QQQQQSSLGN SVMRPPPPPP PPKVKHASSS 420
SSGNSSSSNT NNSSSSSNGE EPSSSIPDLE FDGTTVLCRV CGDKASGFHY GVHSCEGCKG 480
FFRRSIQQKI QYRPCTKNQQ CSILRINRNR CQYCRLKKCI AVGMSRDAVR FGRVPKREKA 540
RILAAMQQST QNRGQQRALA TELDDQPRLL AAVLRAHLET CEFTKEKVSA MRQRARDCPS 600
YSMPTLLACP LNPAPELQSE QEFSQRFAHV IRGVIDFAGM IPGFQLLTQD DKFTLLKAGL 660
FDALFVRLIC MFDSSINSII CLNGQVMRRD AIQNGANARF LVDSTFNFAE RMNSMNLTDA 720
EIGLFCAIVL ITPDRPGLRN LELIEKMYSR LKGCLQYIVA QNRPDQPEFL AKLLETMPDL 780
RTLSTLHTEK LVVFRTEHKE LLRQQMWSME DGNNSDGQQN KSPSGSWADA MDVEAAKSPL 840
GSVSSTESAD LDYGSPSSSQ PQGVSLPSPP QQQPSALASS APLLAATLSG GCPLRNRANS 900
GSSGDSGAAE MDIVGSHAHL TQNGLTITPI VRHQQQQQQQ QQIGILNNAH SRNLNGGHAM 960
CQQQQQHPQL HHHLTAGAAR YRKLDSPTDS GIESGNEKNE CKAVSSGGSS SCSSPRSSVD 1020
DALDCSDAAA NHNQVVQHPQ LSVVSVSPVR SPQPSTSSHL KRQIVEDMPV LKRVLQAPPL 1080
YDTNSLMDEA YKPHKKFRAL RHREFETAEA DASSSTSGSN SLSAGSPRQS PVPNSVATPP 1140
PSAASAAAGN PAQSQLHMHL TRSSPKASMA SSHSVLAKSL MAEPRMTPEQ MKRSDIIQNY 1200
LKRENSTAAS STTNGVGNRS PSSSSTPPPS AVQNQQRWGS SSVITTTCQQ RQQSVSPHSN 1260
GSSSSSSSSS SSSSSSSSTS SNCSSSSASS CQYFQSPHST SNGTSAPASS SSGSNSATPL 1320
LELQVDIADS AQPLNLSKKS PTPPPSKLHA LVAAANAVQR YPTLSADVTV TASNGGPPSA 1380
AASPAPSSSP PASVGSPNPG LSAAVHKVML EA
1413Fasta Sequence
>P13055|Eip75B|Drosophila melanogaster(Fruit fly)
MEAVQAAAAATSSGGSSGSVPGSGSGSASKLIKTEPIDFEMLHLEENERQQDIEREPSSSNSNSNSNSLTPQRYTHVQVQTVPPRQPTGLTTPGGTQKVILTPRVEYVQQRATSSTGGGMKHVYSQQQGTAASRSAPPETTALLTTTSGTPQIIITRTLPSNQHLSRRHSASPSALHHYQQQQPQRQQSPPPLHHQQQQQQQHVRVIRDGRLYDEATVVVAARRHSVSPPPLHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQQQYISTGVPPPTAAARKFVVSTSTRHVNVIASNHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRTEHKELLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRNRANSGSSGDSGAAEMDIVGSHAHLTQNGLTITPIVRHQQQQQQQQQIGILNNAHSRNLNGGHAMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSSGGSSSCSSPRSSVDDALDCSDAAANHNQVVQHPQLSVVSVSPVRSPQPSTSSHLKRQIVEDMPVLKRVLQAPPLYDTNSLMDEAYKPHKKFRALRHREFETAEADASSSTSGSNSLSAGSPRQSPVPNSVATPPPSAASAAAGNPAQSQLHMHLTRSSPKASMASSHSVLAKSLMAEPRMTPEQMKRSDIIQNYLKRENSTAASSTTNGVGNRSPSSSSTPPPSAVQNQQRWGSSSVITTTCQQRQQSVSPHSNGSSSSSSSSSSSSSSSSSTSSNCSSSSASSCQYFQSPHSTSNGTSAPASSSSGSNSATPLLELQVDIADSAQPLNLSKKSPTPPPSKLHALVAAANAVQRYPTLSADVTVTASNGGPPSAAASPAPSSSPPASVGSPNPGLSAAVHKVMLEA
|
| Keyword |
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Interpro |
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001728--ThyrH_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA
|
| PROSITE |
PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2
|
| Pfam |
PF00104--Hormone_recep
PF00105--zf-C4
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0020037--F:heme binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0004887--F:thyroid hormone receptor activity
GO:0008270--F:zinc ion binding
GO:0019730--P:antimicrobial humoral response
GO:0018990--P:ecdysis, chitin-based cuticle
GO:0030522--P:intracellular receptor signaling pathway
GO:0007591--P:molting cycle, chitin-based cuticle
GO:0007275--P:multicellular organismal development
GO:0048477--P:oogenesis
GO:0007553--P:regulation of ecdysteroid metabolic process
GO:0010468--P:regulation of gene expression
GO:0035075--P:response to ecdysone
GO:0006351--P:transcription, DNA-templated
|
