| Tag |
Content |
| dbPAF ID |
dbPAF-0005696 |
| Uniprot Accession |
P12982; PP12_DROME; Q4PIY5; Q9VG75;
|
| Genbank Protein ID |
NP_524937.1;
|
| Genbank Nucleotide ID |
NM_080198.3;
|
| Protein Name |
Serine/threonine-protein phosphatase alpha-2 isoform |
| Protein Synonyms/Alias |
|
| Gene Name |
Pp1-87B |
| Gene Synonyms/Alias |
CG5650; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase.Functional Description
Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase. |
Phosphorylation Sites
|
dbPAF PTMs: 1 | Position | Peptides | Source | References ( PMIDs ) |
|---|
| 46 | KSREIFLSQPILLEL | curated | 22817900 |
|
Sequence
(Fasta) | MGDVMNIDSI ISRLLEVRGA RPGKNVQLSE GEIRGLCLKS REIFLSQPIL LELEAPLKIC 60
GDIHGQYYDL LRLFEYGGFP PESNYLFLGD YVDRGKQSLE TICLLLAYKI KYSENFFLLR 120
GNHECASINR IYGFYDECKR RYSIKLWKTF TDCFNCLPVA AIVDEKIFCC HGGLSPDLTS 180
MEQIRRIMRP TDVPDQGLLC DLLWSDPDKD TMGWGENDRG VSFTFGAEVV AKFLQKHEFD 240
LICRAHQVVE DGYEFFAKRM LVTLFSAPNY CGEFDNAGAM MSVDDTLMCS FQILKPADKR 300
KK
303Fasta Sequence
>P12982|Pp1-87B|Drosophila melanogaster(Fruit fly)
MGDVMNIDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLFSAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKRKK
|
| Keyword |
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0464--Manganese
KW-0479--Metal-binding
KW-0904--Protein phosphatase
KW-1185--Reference proteome
|
| Interpro |
IPR004843--Calcineurin-like_PHP_apaH
IPR029052--Metallo-depent_PP-like
IPR006186--Ser/Thr-sp_prot-phosphatase
IPR031675--STPPase_N
|
| PROSITE |
PS00125--SER_THR_PHOSPHATASE
|
| Pfam |
PF00149--Metallophos
PF16891--STPPase_N
|
| Gene Ontology |
GO:0005700--C:polytene chromosome
GO:0000164--C:protein phosphatase type 1 complex
GO:0046872--F:metal ion binding
GO:0017018--F:myosin phosphatase activity
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0008344--P:adult locomotory behavior
GO:0007411--P:axon guidance
GO:0030261--P:chromosome condensation
GO:0007059--P:chromosome segregation
GO:0007611--P:learning or memory
GO:0040011--P:locomotion
GO:0007080--P:mitotic metaphase plate congression
GO:0007067--P:mitotic nuclear division
GO:0090307--P:mitotic spindle assembly
GO:0000022--P:mitotic spindle elongation
GO:0007399--P:nervous system development
GO:0008355--P:olfactory learning
GO:0048477--P:oogenesis
GO:0006909--P:phagocytosis
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0046579--P:positive regulation of Ras protein signal transduction
GO:0006470--P:protein dephosphorylation
GO:0051225--P:spindle assembly
GO:0008542--P:visual learning
|
