dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0005685 |
| Uniprot Accession | P12945; NAT1_YEAST; D6VRV5; |
| Genbank Protein ID | NP_010244.1; |
| Genbank Nucleotide ID | NM_001180099.1; |
| Protein Name | N-terminal acetyltransferase A complex subunit NAT1 |
| Protein Synonyms/Alias | |
| Gene Name | NAT1 |
| Gene Synonyms/Alias | AAA1;YDL040C;D2720; |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID | 559292 |
| Functional Description (View all) |
Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome and may present the N termini of nascent polypeptides for acetylation. |
| Phosphorylation Sites |
dbPAF PTMs: 6 |
| Sequence (Fasta) | MSRKRSTKPK PAAKIALKKE NDQFLEALKL YEGKQYKKSL KLLDAILKKD GSHVDSLALK 60 GLDLYSVGEK DDAASYVANA IRKIEGASAS PICCHVLGIY MRNTKEYKES IKWFTAALNN 120 GSTNKQIYRD LATLQSQIGD FKNALVSRKK YWEAFLGYRA NWTSLAVAQD VNGERQQAIN 180 TLSQFEKLAE GKISDSEKYE HSECLMYKND IMYKAASDNQ DKLQNVLKHL NDIEPCVFDK 240 FGLLERKATI YMKLGQLKDA SIVYRTLIKR NPDNFKYYKL LEVSLGIQGD NKLKKALYGK 300 LEQFYPRCEP PKFIPLTFLQ DKEELSKKLR EYVLPQLERG VPATFSNVKP LYQRRKSKVS 360 PLLEKIVLDY LSGLDPTQDP IPFIWTNYYL SQHFLFLKDF PKAQEYIDAA LDHTPTLVEF 420 YILKARILKH LGLMDTAAGI LEEGRQLDLQ DRFINCKTVK YFLRANNIDK AVEVASLFTK 480 NDDSVNGIKD LHLVEASWFI VEQAEAYYRL YLDRKKKLDD LASLKKEVES DKSEQIANDI 540 KENQWLVRKY KGLALKRFNA IPKFYKQFED DQLDFHSYCM RKGTPRAYLE MLEWGKALYT 600 KPMYVRAMKE ASKLYFQMHD DRLKRKSDSL DENSDEIQNN GQNSSSQKKK AKKEAAAMNK 660 RKETEAKSVA AYPSDQDNDV FGEKLIETST PMEDFATEFY NNYSMQVRED ERDYILDFEF 720 NYRIGKLALC FASLNKFAKR FGTTSGLFGS MAIVLLHATR NDTPFDPILK KVVTKSLEKE 780 YSENFPLNEI SNNSFDWLNF YQEKFGKNDI NGLLFLYRYR DDVPIGSSNL KEMIISSLSP 840 LEPHSQNEIL QYYL 855 |
| Keyword | KW-0002--3D-structure |
| Interpro | |
| PROSITE | |
| Pfam | PF12569--NARP1 |
| Gene Ontology | GO:0031415--C:NatA complex |